background this retrospective study aimed to determine the epidemiologic characteristics and risk factors of chronic kidney diseases (ckd) in patients < 18 years old at a single referral center. materials and methods in a hospital-based case control study, 66 ckd patients less than 18 years old were compared to 81 control patients (also under 18) without ckd. a patient was defined as a ckd case...

BACKGROUND Chronic kidney disease is an important component of chronic non - communicable diseases that are now of pandemic proportions and are the major cause of morbidity and mortality worldwide. Patients with reduced renal function represent a population not only at risk for progression of kidney disease and development of end stage renal disease (ESRD), but also at a greater risk of cardiov...

world kidney day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. chronic kidney disease (ckd) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relativ...

BACKGROUND Mutation in several podocyte-specific genes have been noted to result in phenotypic heterogeneity. Herein, we report a novel, autosomal dominant TRPC6 mutation in a family with disease ranging from asymptomatic minimal change disease to end-stage kidney disease. CASE PRESENTATION A 35 year old woman developed asymptomatic, nephrotic range proteinuria during pregnancy that did not r...

introduction: kidney disease is a major public health challenge worldwide. epidemiologic data suggest a significant relationship between underlying diseases and decrease in glomerular filtration rate (gfr). clinical studies and laboratory research have shown that the mentioned parameter is effective in development and progression of the renal disease per se. in this study, we used learning-base...

In the early 1970s, mandatory kidney disease screening was started with urinalysis in the Japanese health examination program for all workers and school-age children. In 1983, nationwide urinalysis screening in adults aged > or = 40 yr was mandated in the community-based health examination program. Because glomerulonephritis was an endemic disease and the leading cause of end-stage renal diseas...

INTRODUCTION Involvement of the kidney in children and adolescents with perinatal (HIV-1) infection can occur at any stage during the child's life with diverse diagnoses, ranging from acute kidney injury, childhood urinary tract infections (UTIs), electrolyte imbalances and drug-induced nephrotoxicity, to diseases of the glomerulus. The latter include various immune-mediated chronic kidney dise...