BACKGROUND Despite the stable incidence of end-stage renal disease (ESRD), it continues to be associated with an unacceptably high cardiovascular risk. SUMMARY ESRD is characterized by enhanced oxidative stress and severe inflammation, which boost cardiovascular risk, thus increasing cardiovascular-associated mortality rate. While substantial effort has been made in the technological innovati...

Anaemia is virtually universal, irrespective of aetiology or stage in patients, with Chronic Kidney Disease,including transplant-associated CKD. Anaemia a multi-factorial risk factor for the progression of CKD to End Stage Renal Disease(ESRD), reduces the quality of life and is associated with significant morbidity and mortality. Degree of anaemia is a reflection of severity of chronic kidney d...

Patients with end-stage renal disease (ESRD) often suffer from cardiovascular complications and comorbidities. For example, 55% of ESRD patients suffer from congestive heart failure (CHF) and cardiovascular diseases account for the majority of deaths among ESRD patients (Herzog, Ma, & Collins, 1998; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases;...

Pregnancy is uncommon in women with end-stage renal disease (ESRD). Fertility rates are low in women on dialysis, and physicians still frequently counsel women with ESRD against pregnancy. Advancements in the delivery of dialysis and obstetric care have led to improved live birth rates in women on dialysis, so pregnancy for young women with ESRD is now more feasible and safer. However, these pr...

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A 57-year-old woman with morbid obesity (body mass index 41.6), diabetes mellitus, hypertension and obstructive sleep apnea sought bariatric surgery for weight loss. Her pre-operative serum creatinine was 1.0 mg/dL (88.4 μmol/L), and she had no history of renal calculi. She underwent laparoscopic Roux-en-Y gastric bypass surgery with a 75-cm Roux limb. Post-operatively, she was non-adherent wit...

To assess cardiac status in end-stage renal disease, we compared clinical, ECG, and echocardiographic data from 37 patients on maintenance hemodialysis with data from 42 patients with functioning renal transplants. Cardiovascular symptoms and abnormal cardiovascular findings were more common in dialysis-maintained patients than in those with transplants. Follow-up studies indicated that despite...

OBJECTIVE The study investigated the optimal threshold value of renal arterial resistive index as assessed by Doppler ultrasonography determining chronic kidney disease stage 4 or higher in patients with renal allograft. METHODS In a cross-sectional study the renal arterial resistive index were obtained in interlobar arteries by Doppler ultrasonography in 78 patients with renal allograft. The...

Peritoneal dialysis is the major renal replacement therapy for children with end-stage renal disease, with hemodialysis used for a substantial number of pediatric patients. Reduction of morbidity and mortality is a major goal with the use of these modalities. Adequacy of dialysis and maintenance of peritoneal membrane function are important considerations for children on long term dialysis. Bot...

INTRODUCTION Nephrolithiasis still remains a too frequent and underappreciated cause of end stage renal disease (ESRD). METHODS AND PATIENTS Of the entire cohort of 7128 consecutive patients who started maintenance dialysis in our nephrology department between January 1992 and December 2006, a total of 45 patients (26 women, 19 men) had renal stone disease as the cause of ESRD. The type of ne...