The genus Staphylococcus is composed of Gram-positive bacteria with diameters of 0.5-1.5 μm, characterized by individual cocci that divide in more than one plane to form grape-like clusters [1]. These bacteria are non-motile, nonspore forming facultative anaerobes, featuring a complex nutritional requirement for growth [2-4], a low G+C content of DNA (in the range of 30-40 mol%) [5], a toleranc...

Escherichia coli and Staphylococcus aureus are a serious cause of a variety of communityand hospital-acquired infections. E. coli is one of the most common nosocomial pathogens that cause urinary tract infections (UTIs) and enterocolitis. S. aureus is also an etiological infection agent responsible for significant levels of morbidity and mortality. According to Broad Institute. (2010), Escheric...

Mastitis, a severe infectious disease among dairy cattle, is still a challenge for livestock treatment due to the increased infections by antibiotic resistant strains. Antimicrobial peptides could be the alternate for treating such drug resistant strains. In the present study, the whey proteins extracted from buffalo milk was subjected to enzymatic hydrolysis using trypsin, chymotrypsin, pepsin...

Staphylococcus aureus and some other bacteria are known to cause botryomycosis. These bacteria are known to produce yellowish-white soft grains. Only Actinomadura pelletieri is known to produce red grains. We report here a case of an intensely inflammatory type of botryomycosis. A 35-year-old male labourer presented with swelling, redness and multiple sinuses on his foot, of eight months durati...

In this study Dodecyl trimethyl ammonium sulphate (DTA) was obtained through quaternization reaction between dodecylamine and dimethyl sulfate (yield: 51.5%) while Dimethylamino propyl glucosylamine (DAPGA) was successively synthesized from D-glucose and 3-Dimethylamino propylamine (yield: 93.6%). Both compounds were analyzed through NMR spectroscopy. Evaluation of their biological activity aga...

A series of novel 7-(3-amino-6,7-dihydro-2-methyl-2H-pyrazolo[4,3-c]pyridin- 5(4H)-yl)fluoroquinolone derivatives were designed, synthesized and characterized by 1H-NMR, MS and HRMS. These fluoroquinolones were evaluated for their in vitro antibacterial activity against representative Gram-positive and Gram-negative strains. Results reveal that most of the target compounds exhibit good growth i...

Objective The standard of hygiene in daily life and hospitals can be increased by the use of new antimicrobial fibers, which diminish the danger of pathogenic bacteria. In this study, the antimicrobial effect of special fibers on some staphylococcus isolates was investigated. Materials and Methods The antimicrobial effect of special type of fibers produced in Isfahan Poly Acryl Plant on thre...

Purine nucleoside phosphorylase (PNP; EC: 2.4.2.1) is a key enzyme involved in the purine salvage pathway. A recent bioinformatic study by Yadav, P. K. et al. (Bioinformation 2012, 8(14), 664-672) reports PNP as an essential enzyme and potential drug target in community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). We conducted an analysis using the methodology outlined by the...

background one of the most common nasocomial bacteria is methicillin resistant staphylococcus aureus (mrsa). today, herbal extracts like zataria multiflora from the lamiaceae family are increasingly used. objectives in this study, the antibacterial effect of z. multiflora on 75 strains of was evaluated. materials and methods the strains of staphylococcus aureus were examined for isolation of st...