Overproduction or deficiency of many chaperones and other cellular components cure the yeast prions [PSI+] (formed by Sup35p) or [URE3] (based on Ure2p). However, at normal expression levels, Btn2p and Cur1p eliminate most newly arising [URE3] variants but do not cure [PSI+], even after overexpression. Deficiency or overproduction of Hsp104 cures the [PSI+] prion. Hsp104 deficiency curing is a ...

In the twenty-first century, most high-performance concretes, and many other ordinary concretes, are now based on blended cements that contain silica fume, slag, and/or fly ash additions. Because the chemical shrinkage accompanying the pozzolanic and hydraulic reactions of these mineral admixtures is generally much greater than that accompanying conventional portland cement hydration, these ble...

We examine the gelation of alginate undergoing ionic crosslinking upon ultraviolet (UV) irradiation using in situ dynamic rheology. Hydrogels are formed by combining alginate with calcium carbonate (CaCO3) particles and a photoacid generator (PAG). The PAG is photolyzed upon UV irradiation, resulting in the release of free calcium ions for ionic crosslinking. The viscous and elastic moduli duri...

An average, medium-term, complete success rate (no afib, no antiarrhythmics) of 80% is generally considered very high indeed even for relatively uncomplicated initial catheter ablations for the purpose of curing AF in paroxysmal afibbers. Now Japanese electrophysiologists report that success rates as high as 92% can be achieved simply by reablating conduction gaps making their appearance during...

We report on the control of cyclotrimerization forming a polycyanurate polymer using magnetic iron oxide nanoparticles in an alternating-current (ac) field as an internal heat source, starting from a commercially available monomer. Magnetic nanoparticles were dispersed in the monomer and catalytic system using sonication, and the mixture was subjected to an alternating magnetic field, causing t...

Resin Composites Sandwich restorations and Curing techniques Anders Lindberg, Department of Dental Hygienist Education, Faculty of Medicine, Umeå University, 901 87 Umeå, Sweden. Since the mid-1990s resin composite has been used for Class II restorations in stress-bearing areas as an alternative to amalgam. Reasons for this were the patients’ fear of mercury in dental amalgam and a growing dema...

Propagation of the yeast prion [PSI+], a self-replicating aggregated form of Sup35p, requires Hsp104. One model to explain this phenomenon proposes that, in the absence of Hsp104, Sup35p aggregates enlarge but fail to replicate thus becoming diluted out as the yeast divide. To test this model, we used live imaging of Sup35p-GFP to follow the changes that occur in [PSI+] cells after the addition...

THE EFFECT OF THE BLUE LIGHT DIODE LASER ON SHEAR-PEEL BOND STRENGTH OF ORTHODONTIC BRACKETS WITH VARYING CURING TIME AND DISTANCE Kamran Shaikh, DDS June 17,2010 Background: Light cured composite resin can be time consuming for bonding orthodontic brackets. A new Blue light diode laser may reduce curing times for composite resins. Hypothesis: The laser will achieve similar bond strengths in ha...

Isocyanate-terminated adhesive amphiphilic block copolymers are attractive materials to treat meniscus tears due to their tuneable mechanical properties and good adhesive characteristics. However, a drawback of this class of materials is their relatively long curing time. In this study, we evaluate the use of an amine cross-linker and addition of catalysts as two strategies to accelerate the cu...