This paper extends previously developed 3D SPM for Electrophysiological Source Imaging (Bosch et al., 2001) for neonate EEG. It builds on a prior paper by our group that established age dependent means and standard deviations for the scalp EEG Broad Band Spectral Parameters of children in the first year of life. We now present developmental equations for the narrow band log spectral power of EE...

of focal sources (Sherg and VonCramon, 1985; Schmidt Functional magnetic resonance imaging (fMRI) can et al., 1999). An additional constraint can be derived provide maps of brain activation with millimeter spatial from the assumption that the sources are temporally resolution but is limited in its temporal resolution to uncorrelated (Mosher et al., 1992). These assumptions the order of seconds....

Functional magnetic resonance imaging (fMRI) can provide maps of brain activation with millimeter spatial resolution but is limited in its temporal resolution to the order of seconds. Here, we describe a technique that combines structural and functional MRI with magnetoencephalography (MEG) to obtain spatiotemporal maps of human brain activity with millisecond temporal resolution. This new tech...

This study investigates the relation between walking speed and the distribution of peak plantar pressure and compares a traditional ten-region subsampling (10RS) technique with a new technique: pedobarographic statistical parametric mapping (pSPM). Adapted from cerebral fMRI methodology, pSPM is a digital image processing technique that registers foot pressure images such that homologous struct...

Spatial normalization is an essential preprocessing step in statistical parametric mapping (SPM)-based analysis of PET scans. The standard template provided with the SPM99 software package was originally constructed using (15)O-H(2)O PET scans and is commonly applied regardless of the tracer actually used in the scans being analyzed. This work studies the effect of using three different normali...

In this paper, we describe a temporal model for event-related potentials (ERP) in the context of statistical parametric mapping (SPM). In brief, we project channel data onto a two-dimensional scalp surface or into three-dimensional brain space using some appropriate inverse solution. We then treat the spatiotemporal data in a mass-univariate fashion. This implicitly factorises the model into sp...

Coregistration of functional PET and T1-weighted MR images is a necessary step for combining functional information from PET images with anatomical information in MR images. Several coregistration algorithms have been published and are used in functional brain imaging studies. In this paper, we present a comparison and cross validation of the two most widely used coregistration routines (Fristo...

Functional optical topography (OT) measures the changes in oxygenated and deoxygenated hemoglobin (HbO(2), HHb) across multiple brain sites which occur in response to neuronal activation of the cerebral cortex. However, identification of areas of cortical activation is a complex task due to intrinsic physiological noise and systemic interference and careful statistical analysis is therefore req...

In the present study, we proposed an original and robust methodology which combines the spatial normalization of skeletal muscle images, the statistical parametric mapping (SPM) analysis and the use of a specific parcellation in order to accurately localize and quantify the extent of skeletal muscle damage within the four heads of the quadriceps femoris. T2 maps of thigh muscles were characteri...

UNLABELLED (123)I-FP-CIT ((123)I-N-omega-fluoropropyl-2beta-carbomethoxy-3beta-(4-iodophenyl)nortropane) is a SPECT dopamine transporter (DAT) tracer that probes dopaminergic cell loss in Parkinson's disease (PD). Quantification of (123)I-FP-CIT images is performed at equilibrium using a ratio (BR) of specific (striatal) to nonspecific (occipital) uptake with values obtained from regions of int...