In this paper we investigate systematic sampling in the imagesynthesis context. Systematic sampling has been widely used in stereology to improve the efficiency of different probes in experimental design. These designs are theoretically based on estimators of 1-dimensional and 2-dimensional integrals. For the particular case of the characteristic function, the variance of these estimators has b...

The investigations on ceramic foams with porous, heterogeneous microstructure are based the standards and dimensions for dense materials due to lack of alternatives. It is known that variations in pore size, shape porosity have a significant effect physical properties, however, considered sample volume treated here as secondary interest. To determine representative volume-of-interest (REVOI), i...

BACKGROUND Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on heart function and survival. Despite already available digital methods, the pathologist's visual score is still widely considered as ground truth and used as a primary method in histomorphometric evaluations. The aim of this study was to compare the accuracy of digital image analysis tools and the pa...

In 2 studies, a method of linear morphometry was applied to regulatory developmental neurotoxicity studies in the rat. The first study involved the development of the brain during postnatal days (PNDs) 7-63, and the second involved the effects of 8 mg/kg i.p. trimethyltin chloride (TMT) to rats at PND 8, with morphometry performed at PNDs 12 and 24. The results of the TMT linear morphometry wer...