Stevens-Johnson syndrome (SJS) is a hypersensitivity reaction that affects the skin and mucous membranes. In this case report patient had drug induced after taking treatment for bilateral leg edema, was hospitalized later diagnosed as SJS. Upon evaluation, increased serum creatinine, decreased albumin, urinary output almost an uric edema which are signs of acute kidney injury (AKI), common comp...

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Uma abordagem enantiosseletiva eficiente para a preparação de centros quaternários a partir da prolina 5 foi desenvolvida através do rearranjo [2,3]-sigmatrópico de Stevens, co-catalisado por líquido iônico. O rearranjo sigmatrópico foi estereoespecífico porque as migrações-[2,3] foram restritas à mesma face e a estereosseletividade surgiu na etapa preliminar da N-alquilação em 8. O método most...

BROWN, D. M., and ACRED, P. (I96I): ' Penbritin '-a New Broad Spectrurn Antibiotic, Brit. med. J7., ii, I97. KNUDSEN, E. T., ROLINSON, G. N., and STEVENS, S. (I96I): Absorption and Excretion of ' Penbritin ', Ibid., ii, I98, ROLINSON, G. N., and STEVENS, S. (I96I): Microbiological Studies on a New Broad Spectrum Penicillin-' Penbritin', Ibid., ii, I9I. SEABURY, J. H., and DASCOMB, H. E. (1958):...

Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening conditions associated with significant morbidity and mortality. They are considered to be part of a spectrum of cutaneous drug reactions, differing only by their extent of skin detachment due to keratinocyte apoptosis. Drugs are assumed as the main cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in mos...