the objective of this study was to determine and compare cystatin c changes before and after radiotherapy in patients with stomach cancer who were candidate for radiotherapy. this study was conducted as a prospective cohort one. eighteen patients with definite diagnosis of stomach cancer under treatment by radiotherapy who presented to radiotherapy-oncology center of imam hossein hospital, tehr...

background: worldwide, cancer of stomach is still the fourth common cancer and the second cause of mortality among all cancers affecting annually 870,000 subjects. this study aims to determine the frequency and the characteristics of gastric cancer in southern iran. materials and methods: 10,800 of all cancers registered in fars hospital-based cancer registry were surveyed among which 574 cases...

conclusions abnormal e-cadherin expression is a common phenomenon in gastric adenocarcinoma. the study showed a significant correlation between abnormal e-cadherin expression and tumor grade and regional lymph node involvement; so, abnormal e-cadherin expression may be used as a predictive factor for tumor invasiveness in gastric adenocarcinoma. materials and methods a historical cohort survey ...

BACKGROUND To explore whether combined detection of serum tumor markers (CEA, CA72-4, CA19-9 and TSGF) improve the sensitivity and accuracy in the diagnosis of gastric cancer (GC). MATERIALS AND METHODS An automatic chemiluminescence immune analyzer with matched kits were used to determine the levels of serum CEA, CA72-4, CA19-9 and TSGF in 45 patients with gastric cancer (GC group), 40 patie...

The occurrence of lymph node metastases (LNM) after endoscopic submucosal dissection (ESD) in patients with gastric cancer (GC) leads to poor prognosis. However, few biomarkers are available to predict LNM in GC patients. Thus, we measured expression of 6 cancer-related miRNAs using real-time RT-PCR in 102 GC samples that were randomized into a training set and a testing set (each, 51 cases). U...

It is uncommon for gastric cancer to present clinically with symptoms attributable to distant metastases. This report describes 3 cases of carcinoma of the greater curvature and the posterior wall of the stomach that presented as metastases to the skin, bone, and lungs. In patients with adenocarcinoma of unknown origin, a gastric primary tumour, especially one along the greater curvature and po...

BACKGROUND AND STUDY AIM Endoscopic resection for early gastric cancers that meet the expanded indication is considered to be an investigational treatment. The study aim was to evaluate long-term outcomes of endoscopic resection compared with surgery for early gastric cancers meeting the expanded indication. METHODS We retrospectively reviewed data from patients who underwent endoscopic resec...

Gastric cancer often carries a poor prognosis, with an estimated 740,000 deaths from the malignancy occurring yearly worldwide (Dicken et al., 2005). The mortality of disease is largely dependent on the extent of tumor spread, as gastric cancer has a predilection to metastasize to other visceral secondaries via hematogenous and lymphatic dissemination. Direct invasion of a gastric adenocarcinom...