The Food and Drug Administration (FDA) draft guidance on adaptive design randomized clinical trials provides in-depth consideration of the difficulties that unblinded adaptation of clinical trial design might introduce. We provide extended discussion of these difficulties, with focus on the problems that the adaptive designs pose in the scientific interpretation of randomized clinical trial res...

This paper describes “Empowering Minds,” a collaboration between the MIT Media Laboratory, St. Patrick’s College, and Irish primary school teachers. In this project, we are introducingLEGO Mindstorms technology into Irish primary schools, along with a framework for teacher professional development that centrally recognizes teachers’ passions and interests in bringing about pedagogical change.

Wie wenig die klassischen Wissensmanagement-Methoden die Bedeutung des sozialen Kontextes berücksichtigen, zeigt sich auch beim Thema des Wissenstransfers. ITgestützte Projektdokumentationen und dergleichen leisten gute Dienste, wenn es um die Dokumentation und Verbreitung von leicht verbalisierbarem Faktenwissen geht. Doch das schwer verbalisierbare Wissen über soziale Aspekte und kulturelle B...

T heologian John Shea, STD, writing several years ago about CHA's Mission-Centered Leadership Competency Model, said that in health ministry the first step from faith to practicality—that is, concrete action on behalf of mission—is values. "Faith convictions and narratives are expressed in the full-blown religious language of the Catholic tradition, for example, God, Christ, sin, redemption, ch...

Though utilizing information from the internet is common in language learning, it is often a spontaneous behavior and is not supported by computer programs that are specialized for language learners. In this project, we create a collaborative learning environment for Mandarin Chinese that implements the idea of learning by teaching. The students will learn and practice their language skills by ...

Photo collections are one of the promising sources to tell story of life in this digital era. In this paper we present our work on organizing photos of a lifetime by exploiting semantic annotations. The complexity in using semantic technology is managed by introducing an annotation template corresponding to who, when, where, and what. Semantics of each dimension are semi-automatically annotated...

This paper explores the contentious notion of experiential narrative and proposes the first step in a narrative framework for game environment. It argues for a shift in emphasis from story-telling, the dominant mode of narrative in literature and cinema, to story generation. To this effect the paper forwards a perspective on experiential narrative that is grounded in the specific qualities of t...

As computer games adopt larger, more life-like virtual worlds, socially believable characters become progressively more important. Socially believable non-player characters (NPCs) must be able to act in social situations and communicate with human players. In this paper, we address one aspect of social believability: the construction and telling of alibi stories, or an artificial background tha...