Two pathways are known to exist for glutamate oxidation in liver mito chondria. One is by way of glutamate dehydrogenase [EC 1.4.1.3.] reaction and the other by aspartate transaminase [EC 2.6.1.1.] reaction. Although both enzyme activities are high in mitochondrial fraction, it is known that glutamate is pre ferentially oxidized through the transaminase pathway in isolated intact mito chondria ...

The oxygen that a wine receives during the winemaking process defines its properties. aim of this work was to evaluate consumption capacity wines and influence on modification their composition. This preliminary evaluated changes after 3 months in chemical composition twenty-seven Spanish commercial red, white rosé air saturation oxidation at 35 °C for 7 days. All studied were high consumers, w...

This booklet consists of the addresses delivered at the opening of the new laboratory for biochemical research at McLean Hospital. Cecil K. Drinker reviews the history of research at McLean Hospital. Jordi Foich surveys biochemical research in psychiatry with emphasis on his own contributions to the chemical constitution of the brain. The record of reasearch at the Psychiatric Service of the Ma...

Propionic acid was one of the early products observed as resulting from bacterial action. Kearly 70 years ago (1854) Strecker (I) reported it as resulting from a fermentation of mannitol which he had studied, while Pasteur (2) also found propionic acid as one of the products formed in the fermentation of calcium tartrate. As these early observations were not made upon pure cultures, it is impos...

About the year 1846 Gobley succeeded in obtaining from egg yolk and other organs a substance of a fat-like nature containing nitrogen and phosphorus which he called lecithin [1846]. This substance was soluble in alcohol and in ether, formed an emulsion when rubbed up with water and yielded fatty acids and glycerophosphoric acid on hydrolysis. These observations of Gobley furnished a basis for t...

Neutral oligosaccharides were released by alkaline sodium borohydride reduction of the jelly coating from the South African clawed toad, Xenopus laevis. The oligosaccharides were isolated by HPLC and analyzed by matrix-assisted laser desorption ionization (MALDI)-Fourier transform mass spectrometry (FTMS). The mass spectrometry analysis allowed confirmation of 12 structures first proposed by St...