Structural variations (SV) are broadly defined as genomic alterations that affect >50bp of DNA, which are shown to have significant effect on evolution and disease. The advent of high throughput sequencing (HTS) technologies and the ability to perform whole genome sequencing (WGS), makes it feasible to study these variants in depth. However, discovery of all forms of SV using WGS has proven to ...

We present near-infrared K-band spectroscopy of 21 elliptical or cD Brightest Cluster Galaxies (BCGs), for which we have measured the strength of the 2.293 µm CO stellar absorption feature. We find that the strength of this feature is remarkably uniform among these galaxies, with a smaller scatter in equivalent width than for the normal elliptical population in the field or clusters. The scatte...

Zfy-1 and Zfy-2 are candidate genes for Tdy, the testis-determining gene in mice. We have analysed these genes in a line of XY female mice that have been shown to be mutated in Tdy. We have used Southern blot analysis to show that the Zfy genes have not undergone any major structural alterations, and have also demonstrated that both genes are transcribed normally from the mutant Y chromosome (Y...

Keywords Androgenetic Embryo An embryo with two paternal genomes, and no maternal genome, produced by nuclear transplantation. Chromatin DNA packaged around nucleosomes. The degree of packaging differs between active (euchromatic) and inactive (heterochromatic) chromosomal regions.

Citation: Firrao G, Torelli E, Polano C, Ferrante P, Ferrini F, Martini M, Marcelletti S, Scortichini M and Ermacora P (2018) Genomic Structural Variations Affecting Virulence During Clonal Expansion of Pseudomonas syringae pv. actinidiae Biovar 3 in Europe. Front. Microbiol. 9:656. doi: 10.3389/fmicb.2018.00656 Genomic Structural Variations Affecting Virulence During Clonal Expansion of Pseudo...

Manoj Kumar,1 Tushar Agarwal,2 Punit Kaur,3 Manoj Kumar,3 Sudarshan Khokhar,2 Rima Dada1 Affiliations: 1Laboratory for Molecular Reproduction and Genetics, Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India 2Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India 3Department of Biophysics, All India Institute of...

Arracacia xanthorrhiza is an important secondary food crop in South America and Puerto Rico. The lack of crop protection and improvement strategies leads to infections damaging the storage roots. Here, we report the annotated complete chloroplast genome sequence of A. xanthorrhiza as a step toward developing genomic resources for this crop.

A small fast neutron (FN) mutant population has been established from Phaseolus vulgaris cv. Red Hawk. We leveraged the available P. vulgaris genome sequence and high throughput next generation DNA sequencing to examine the genomic structure of five P. vulgaris cv. Red Hawk FN mutants with striking visual phenotypes. Analysis of these genomes identified three classes of structural variation (SV...

Genomic libraries derived from environmental DNA (metagenomic libraries) are useful for characterizing uncultured microorganisms. However, conventional library-screening techniques permit characterization of relatively few environmental clones. Here we describe a novel approach for characterization of a metagenomic library by hybridizing the library with DNA from a set of groundwater isolates, ...

Arcobacter butzleri is considered to be an emerging human foodborne pathogen. The completion of an A. butzleri genome sequence along with microarray analysis of 13 isolates in 2007 revealed a surprising amount of diversity amongst A. butzleri isolates from humans, animals and food. In order to further investigate Arcobacter diversity, 792 faecal samples were collected from cattle on beef and da...