Alkoxyamines of TEMPO usually dissociate thermally at >100 °C; however, room temperature homolysis, activated by visible light, occurs with benzimidazolequinone derivatives. 1,1’-Dimethyl-2,2’-bis{[(2,2,6,6-tetramethylpiperidin-1-yl)oxy]methyl}-6-(trifluoromethyl)-1H,1’H-[5,5’-bibenzimidazole]-4,4’,7,7’-tetrone (CF3-Bis-TEMPO-Vis) is prepared in a 59% yield through NBS/H2SO4 oxidative demeth...

A series of binuclear aluminum complexes 1–3 supported by tridentate phenoxyimino-phenoxy ligands was synthesized and used as catalysts for the coupling reaction terminal epoxide with carbon dioxide. The complex 1, which is catalytically inactive toward CO2 itself, shows moderate activity in presence excess nucleophiles or organic bases at high temperature. In sharp contrast to bifunctional 2 3...

The metabolism of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene (BP-7,8-diol) by prostaglandin synthetase and cytochrome P-450-dependent monooxygenases was studied using enriched fractions of Clara cells and alveolar type II cells from rat lung. Arachidonic acid-fortified fractions enriched in Clara cells and alveolar type II cells metabolized BP-7,8-diol to the 7,10/8,9-tetrol of benzo(a...

The mol-ecule of the title compound, C(15)H(12)N(2)O(4), adopts a syn conformation with the terminal benzene rings located on the same sides of the central epoxide ring. The epoxide ring makes dihedral angles of 71.08 (18) and 60.83 (17)° with the two benzene rings. Weak inter-molecular C-H⋯O hydrogen bonding is present in the crystal structure.

The curing of epoxy-anhydride vitrimers involves anionic copolymerization epoxide and anhydride along with homopolymerization excess epoxide, giving rise to a poly(ester-co-ether) network. By monitoring using infrared spectroscopy in different conditions mapping the presence OH groups, we demonstrate that generation hydroxide necessary for transesterification, exclusively relies on side reactio...

Hydrosilylation of alkenes with epoxide-terminated tri(ethylene oxide) moieties on Si-H surfaces yields homogeneous monolayers for the efficient coupling of biomolecules. The wetting properties of the epoxide-functionalized surface allow for the spotting of solutions of biomolecules, making the surface amenable to microarraying. Immobilization of thiolated DNA was achieved in a single step to f...

2-Amino-N-isopropylacetamide and α-amino-ε-caprolactam were reacted with glycerol diglycidyl ether to give novel oligomeric thermoresponsive epoxide-amine adducts. These oligomers exhibit a lower critical solution temperature (LCST) behavior in water. The solubility properties were influenced with randomly methylated β-cyclodextrin (RAMEB-CD) and the curing properties of the amine-epoxide mixtu...

Microsomal epoxide hydrolase was purified to homogeneity from phenobarbital-induced rabbit liver for the purpose of determining the complete amino acid sequence. All of the expected 11 cyanogen bromide fragments of epoxide hydrolase were isolated by a combination of gel filtration and high pressure liquid chromatography. Each was characterized by its amino acid composition and NH2-terminal amin...