Choroidal melanoma is the most common primary intraocular malignancy in adults. Herein, authors report two cases of subretinal hemorrhage associated with it. The first case presented a large choroidal mass hemorrhage, no history trauma and diagnosis on ultrasound. second was initially diagnosed retinal detachment but during surgery pigmented observed, starting to bleed after scleral depression....

Newer glycemic agents, specifically glucagon-like peptide 1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter 2 inhibitors (SGLT2i), have proven cardiorenal benefits. Despite this strong evidence of benefits, uptake has been poor. We examined (1) the geographic variations associated with use GLP-1RA or SGLT2i compared to dipeptidyl peptidase 4 (DPP-4i) sulfonylureas (SFU) (2) initiat...

BACKGROUND To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD). METHODS Data from healthy subjects and patients diagnosed with AMD or other retinal diseases were collected during routine visits via an Electronic Health Record (EHR) system. Patien...

PURPOSE Pinealitis accompanying uveitis is well established in laboratory models of experimental autoimmune uveoretinitis. In naturally occurring uveitis, pinealitis has been demonstrated in the pineal gland from a mare with active uveitis and is suspected in some human uveitides. We have evaluated pineal glands from horses with various stages of uveitis for signs of immunopathology accompanyin...

Uveitis is a clinical feature of the Blau syndrome, a disease linked to CARD15 (also referred to as NOD2) mutations. Three main mutations in this gene (R334W, R334Q and L469F) have been reported as Blau syndrome risk factors, a disease that manifests uveitis as one of its clinical features. However, little is known on the involvement of this gene in idiopathic uveitis. We thus sought to determi...

Ground-based spectrographical observations of infrared emissions of the mesopause region have been made at Zvenigorod Observatory (56 N, 37 E), located near Moscow, Russia, for 670 nights of 2000–2006. The characteristics of the hydroxyl and molecular oxygen (865 nm) airglow, heights of which correspond to 87 and 94 km, are analyzed for finding their response to solar activity. The measured dat...

A standard 23-gauge or 25-gauge valved trocar is positioned externally next to the sclera at an area corresponding to the most elevated retina. During internal visualization, the trocar is advanced at an angle of 15°, penetrating the sclera and the choroid, and entering the subretinal space (Figure 2). Once it has been visually confirmed that the cannula entered the subretinal space, the trocar...

purpose : to investigate the risk factors and causes for blindness in behcet’s disease (bd). methods : in this preliminary retrospective case series we have investigated 27 bd patients (54 eyes), legally blind (vision 0.1 or less) at least in one eye at the last visit (2006), and compared them with 54 eyes of 27 non-blind patients (control group), matched individually and consequently in terms ...

This paper describes the SFU entry for the TRECVid 2009 event detection challenge. We attempted to detect events involving either one or two individuals, and present algorithms for “running”, “embrace”, and “pointing” event detection. The system has three stages. First, preprocessing is performed to extract candidate space-time regions using background subtraction and photogrammetric context. T...

This paper describes the SFU entry for the TRECVid 2010 surveillance event detection challenge. We focus on detecting the ”PresonRuns” event. The system has three stages. First, a pre-processing step is performed to extract moving candidate space-time regions using background subtraction, optical flow, and photogrammetric context. A short clip representation is constructed for each moving candi...