نتایج جستجو برای: substantial nigra

تعداد نتایج: 147087  

Journal: :Experimental neurology 2003
Min-Qin Ren Wei-Yi Ong Xin-Sheng Wang Frank Watt

The present study was carried out to elucidate the concentration and distribution of iron in the substantia nigra of two age groups of monkeys after experimental hemi-Parkinsonism induced by unilateral internal carotid injections of MPTP. Iron levels and distribution were detected using the nuclear microscope, which is able to provide structural and quantitative elemental analysis of biological...

Journal: :Brain : a journal of neurology 1999
P Damier E C Hirsch Y Agid A M Graybiel

Parkinson's disease is characterized by massive degeneration of dopamine-containing neurons in the midbrain. However, the vulnerability of these neurons is heterogeneous both across different midbrain dopamine-containing cell groups and within the substantia nigra, the brain structure most affected in this disease. To determine the exact pattern of cell loss and to map the cellular distribution...

2010
W. Michael Panneton V. B. Kumar Qi Gan William J. Burke James E. Galvin

BACKGROUND The etiology of Parkinson disease (PD) has yet to be fully elucidated. We examined the consequences of injections of 3,4-dihydroxyphenylacetaldehyde (DOPAL), a toxic metabolite of dopamine, into the substantia nigra of rats on motor behavior and neuronal survival. METHODS/PRINCIPAL FINDINGS A total of 800 nl/rat of DOPAL (1 µg/200 nl) was injected stereotaxically into the substanti...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2004
Matteo Marti Flora Mela Carlo Veronesi Remo Guerrini Severo Salvadori Mauro Federici Nicola B Mercuri Anna Rizzi Gianfranco Franchi Lorenzo Beani Clementina Bianchi Michele Morari

A multidisciplinary approach was followed to investigate whether the opioid-like peptide nociceptin/orphanin FQ (N/OFQ) regulates the nigrostriatal dopaminergic pathway and motor behavior. Nigrostriatal dopaminergic cells, which express N/OFQ peptide (NOP) receptors, are located in the substantia nigra pars compacta and extend their dendrites in the substantia nigra pars reticulata, thereby mod...

Journal: :The Journal of pharmacology and experimental therapeutics 1999
Z B You M Herrera-Marschitz L Terenius

Microinjection studies have found that although dynorphin peptides decrease dopamine release in the rat basal ganglia, the nonselective opiate antagonist naloxone produces the opposite effect. To investigate the contribution of the dynorphin pathways to a tonic modulation of dopamine release, a microdialysis study was undertaken, with probes implanted in the substantia nigra and the ipsilateral...

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مقاله حاضر شامل سه طرح تحقیقاتی در سه منطقه ارتفاعی در استان گیلان است. در منطقه ارتفاعی پایین‌بند به ارتفاع 450 متر در جنگل‌های اسالم واقع در طرح سیاه‌بیل شماره یک، 13 گونه و پروونانس مورد آزمایش قرار گرفته است. در منطقه میان‌بند واقع در طرح ناو اسالم به ارتفاع 1050 متر، 15 گونه و پروونانس و در منطقه بالابند به ارتفاع 1750 متر واقع در طرح ناو اسالم، 9 گونه و پروونانس کشت گردید. در هر منطقه طرح...

Journal: :ACS Chemical Neuroscience 2019

Journal: :Journal of Clinical Pathology 1969

Journal: :Österreichische Botanische Zeitschrift 1890

Journal: : 2022

Indirect Estimation of Genetic Structure and Gene Flow in Some Black Poplar (Populus Nigra) Clones using Leaf Morphophysiological Traits

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