Health technology The use of fentanyl, sufentanil and remifentanil for fast-track cardiac anaesthesia was investigated. The patients in the fentanyl group received fentanyl 7 to 10 microg/kg for induction and additional doses of 1 to 2 microg/kg (as needed) for intense stimulus. The patients in the sufentanil group received sufentanil at doses of 1 to 4 microg/kg for induction and 0.1 to 0.3 mi...

BACKGROUND The aim of this study was to assess the preventative effect of ketamine on the exaggerated postoperative pain observed in sufentanil-treated mice and its ability to improve the analgesic effectiveness of morphine during the postoperative period in an orthopaedic model of pain. METHODS In this study, we assessed the effects of ketamine on sufentanil enhancement of pain behaviour ind...

OBJECTIVES Cardiac surgery involving cardiopulmonary bypass is associated with neurologic deterioration. Several interventions, including anesthetic techniques, have been designed to limit ischemic brain damage and have been evaluated in animals. Markers of neurologic injury may facilitate the assessment of these interventions in humans. DESIGN A blinded randomized prospective study comparing...

Purpose: We evaluated the effect of adding Sufentanil to mixture Lidocaine and Bupivacaine used for supraclavicular brachial plexus block in reducing postoperative pain.
 Method: This double-blind clinical intervention trial was conducted 2007. Patients scheduled undergo upper limb orthopedic surgeries under were recruited. Participants one arm given Sufentanil, lidocaine, bupivacaine (Gro...

Previously it has been shown in rats that both ketamine and morphine induced analgesia and, at larger doses, catalepsy and loss of the righting reflex, all of which were reversed by naloxone at widely different doses. Tolerance developed rapidly to either ketamine or morphine and there was cross-tolerance from ketamine to morphine. However, morphine potentiated the cataleptic effect of ketamine...

BACKGROUND Anesthesia induction in patients with current substance abuse can be a challenge for anesthesiologists. OBJECTIVES This study aimed to evaluate the effect of adding Sufentanil to Bupivacaine on duration of brachial plexus nerve block. PATIENTS AND METHODS One hundred and twenty patients with (Groups C and D) and without (Groups A and B) a history of opium abuse (60 in each group)...

BACKGROUND AND OBJECTIVES Dexmedetomidine, alpha2-adrenergic agonist with alpha1:alpha2 specificity of 1:1620, does not promote respiratory depression and is intraoperatively used for sedation and analgesia. It has been used associated to opioids in anesthesia for procedures with high painful stimulation, such as intraperitoneal surgeries, and there are no references to its use as single agent....

Pain management is crucially important in the postoperative period as it increases patient comfort and satisfaction. The primary outcome of present study was to evaluate the effect of sufentanil added to hyperbaric bupivacaine solution 0.25% in transversus abdominis plane (TAP) block, on postoperative analgesic consumption. Fifty ASA physical status I-II term primiparous single-tone pregnant wo...

BACKGROUND AND OBJECTIVES Shivering is a cause of discomfort and dissatisfaction in patients undergoing cesarean section. The objective of this study paper was to assess the impact of intrathecal administration of sufentanil on the incidence of shivering after cesarean section. METHOD In a prospective blinded, randomized clinical trial, pregnant women undergoing cesarean section under spinal ...

The bispectral index (BIS) and a sedation score were used to determine and compare the effect of propofol in the presence of fentanyl, alfentanil, remifentanil and sufentanil. Seventy-five non-premedicated patients were assigned randomly into five groups (15 in each) to receive fentanyl, alfentanil, remifentanil, sufentanil or placebo. Opioids were administered using a target-con-trolled infusi...