Both singlet oxygen and the hydroxyl radical are generated in mammalian ccHs by UVA (~3Z0---~3{50 rim) and possibly near-visible (~{50--420 nm) radiation. We have modulated the cellular levels of these two reactive oxygen species in order to compare their involvement in the induction of the human heme 0xygenase (I40) gene by broad spectrum UVA/nearvisible light 0LIVA/NVL). Irradiation in deuter...

A novel fluorescent nanosensor has been developed by combining super fluorescence quenching ability of graphene oxide and hybridization chain reaction amplification, which enables highly sensitive detection of base excision repair enzyme activity with a wide dynamic range from 0.0001 to 100 U mL(-1) and a detection limit of 0.00006 U mL(-1).

BACKGROUND The recent literature suggests that free radicals and reactive oxygen species may account for many pathologies, including those of the nervous system. MATERIALS AND METHODS The influence of various reactive oxygen species on the rate of glutamate uptake by astrocytes was investigated on monolayers of primary cultures of mouse cortical astrocytes. RESULTS Hydrogen peroxide and per...

A (super)critical transfer: The consecutive hydrogenolysis and hydrogenation of the lignin model compound dihydrobenzofuran was studied in supercritical methanolic solutions using porous metal oxide catalysts. These catalysts promote H(2) production from methanol followed by hydrogenolysis of the ether linkages and reduction of the aromatic rings, leading principally to a mixture of cyclohexanols.

Three stilbene trimers (gnemonols D, E, F) were isolated from the root of Gnetum gnemon. The structures were determined by spectroscopic analysis. In addition, the antioxidant activity of the compounds on lipid peroxide inhibition and super oxide scavenging activity were also investigated.

A novel amplified fluorescence graphene oxide (GO) sensing platform for sensitive detection of T4 polynucleotide kinase (PNK) activity and inhibition was developed based on the exonuclease III (ExoIII) reaction. The efficient digestion capacity of ExoIII and the super quenching ability of GO both contribute to the detection sensitivity.

Alcoholic extract of pericarp showed significant protection against FeSO4 induced lipid peroxidation, as compared with whole native nut and seeds. Mechanism of action may be through metal chelation or activation of endogenous antioxidant enzymes, because the extract did not show hydroxyl and super oxide anion scavenging property. Further in vitro experiments against FeSO4, it did not maintain t...

In the past decades, there is a growing interest in the design and synthesis of composite microspheres with a dielectric solid sphere (e.g., silica, polystyrene) covered by metallic and their corresponding metal oxides shell, such as copper[1], gold[2], silver[3,4], iron oxide[5], zinc oxide[6,7], titanium oxide[8,9] and zirconium dioxide[10]. Such materials may exhibit a few unique electrical,...

Oxide scale thickness measurements are used in assessing the life of different components operating at high temperature environment. Such measurements provide an approximation for the temperature inside components such as reheater and superheater tubes. A number of failures were encountered in one of the boilers in one of Kuwaiti power plants. These failure were mainly in the first row of the p...

In the past decades, there is a growing interest in the design and synthesis of composite microspheres with a dielectric solid sphere (e.g., silica, polystyrene) covered by metallic and their corresponding metal oxides shell, such as copper[1], gold[2], silver[3,4], iron oxide[5], zinc oxide[6,7], titanium oxide[8,9] and zirconium dioxide[10]. Such materials may exhibit a few unique electrical,...