MOTIVATION A major challenge in utilizing microarray technologies to measure nucleic acid abundances is 'normalization', the goal of which is to separate biologically meaningful signal from other confounding sources of signal, often due to unavoidable technical factors. It is intuitively clear that true biological signal and confounding factors need to be simultaneously considered when performi...

Motivation: The advent of new genomic technologies has resulted in the production of massive data sets. Analyses of these data require new statistical and computational methods. In this article, we propose one such method that is useful in selecting explanatory variables for prediction of a binary response. Although this problem has recently been addressed using penalized likelihood methods, we...

Summary We present a web server running the MIIC algorithm, a network learning method combining constraint-based and information-theoretic frameworks to reconstruct causal, non-causal or mixed networks from non-perturbative data, without the need for an a priori choice on the class of reconstructed network. Starting from a fully connected network, the algorithm first removes dispensable edges b...

BACKGROUND Assessing ethical endorsement is crucial to the study of professional performance and moral conduct. There are no specific instruments that verify patients and professional experiences of ethical practice in the specific area of primary health care (PHC). OBJECTIVE To study the psychometric properties of two questionnaires to identify professional and patient endorsement of normati...

MOTIVATION Until now, much of the focus in cancer has been on biomarker discovery and generating lists of univariately significant genes, as well as epidemiological and clinical measures. These approaches, although significant on their own, are not effective for elucidating the synergistic qualities of the numerous components in complex diseases. These components do not act one at a time, but r...

This study deals with effects of supplementary feeding on fertility performance of Farahani ewes. The study was conducted using three local flocks in Arak city, Iran. Half ewes in each flock (50 ewes from each flock) were used as control group and fed according to traditional method without supplementary feed. The other half per flock was fed on supplementary feed throughout the experiment that...

About two-thirds of the 6.1 billion people living in globe rely on healing power plant-based materials. ‘Nutraceuticals’ are apart from herbal items, dietary supplements, certain diets, and processed foods like cereals, soups, drinks that used for medical purposes addition to being a source nourishment. It plays vital role day life example green tea. involves probiotics prebiotics, medicinal in...