J. Hertz Nordita Blegdamsvej 17 2100 Copenhagen 0 Denmark The problem of learning from examples in multilayer networks is studied within the framework of statistical mechanics. Using the replica formalism we calculate the average generalization error of a fully connected committee machine in the limit of a large number of hidden units. If the number of training examples is proportional to the n...

DNA samples collected in clinical trials and stored for future research are valuable to pharmaceutical drug development. Given the perceived higher risk associated with genetic research, industry has implemented complex coding methods for DNA. Following years of experience with these methods and with addressing questions from institutional review boards (IRBs), ethics committees (ECs) and healt...

Conventional wisdom suggests that CEO membership of the compensation committee is an open invitation to rent extraction by self-serving executives. However, using data from New Zealand – where CEO compensation committee membership is relatively common – we find that annual pay increments for CEOs with this apparent advantage averaged six percentage points less than those enjoyed by other CEOs d...

This symposium provided a useful forum for the discussion of issues relating to the design and conduct of clinical trials. There is a need for greater awareness of the complexity of modern day trials, in which a host of statistical, logistical, regulatory and ethical issues are involved. Issues discussed ranged from the effect of sample size on the outcome, and subgroup analysis, to defining an...

This study aims to describe the contribution of School Committee in improving quality Islamic religious education at MTsN Solok City. The Committee, which should carry out its duties and functions properly is still faced with many problems so that general Religious Education (PAI), especially madrasa, has not shown expected results. research field (field research). approach used a qualitative a...

abstract background: chronic renal disease and hemodialysis cause numerous psychological, social, cultural, and spiritual challenges for both patients and their families. overcoming these challenges is possible only through providing holistic support for the patients. today, despite the support provided by family and professional caregivers for the patients, patients still express dissatisfacti...

the study objects for investigating the possibility of activating both audit committee and board of directors for restricting the practices of earnings management phenomenon. to achieve this objective, a questionnaire had been developed and self-administered for a selected sample consists of 123 auditors working in jordan based on the simple random sampling method. the study first hypothesis is...

Data and Safety Monitoring Boards (DSMBs) are commonly appointed to monitor emerging data from major clinical trials. This paper describes their organization and remit, and their relationship with other trial committees and structures. The operation of formal stopping rules for safety and efficacy by a DSMB is discussed. The duties of a DSMB, from pre-trial planning through to stopping a study ...

In table 1 of this Feature (BMJ 2013;346:f3037, doi:10.1136/ bmj.f3037), we would like to add a note that the surgeon general recommended, in 1960, that all pregnant women be vaccinated. The Centers for Disease Control and Prevention first made a specific recommendation for pregnant women in their second and third trimesters in 1997 (not 2000, as stated in the table), and expanded this to all p...