OBJECTIVE This retrospective study evaluated the efficacy and safety of the use of Gamma Knife Radiosurgery (GKS) along with other surgical procedures in the management of craniopharyngioma. METHODS Thirty-five patients (17 children and 18 adults) with craniopharyngioma were treated with GKS between May 2008 and August 2011. The age of the patients ranged from 2 to 53 years (mean 20 years). T...

Stereotactic radiosurgery is an emerging treatment option offered to patients with glioblastoma (GB). Radiosurgery is performed as an outpatient procedure and provides a safe and effective non-invasive treatment for focal GB. High-energy beams originating from cobalt sources placed into a helmet-shaped device (Gamma Knife®, Elekta) or generated by a linear accelerator (LINAC), rotating on a gan...

PURPOSE This study investigated the effectiveness of a clamp method combined with bipolar coagulation for anatomical hepatectomy in the treatment of hepatocellular carcinoma (HCC). METHODS In this prospective case-control study, three liver dissection methods were used: clamping combined with bipolar electric coagulation (group A), CUSA (Cavitron ultrasonic surgical aspirator) (group B), and ...

AIM To observe the outcomes of 1H- MR-spectroscopy (MRS) guided gamma knife surgery for treatment of glioma. MATERIAL AND METHODS Twenty patients with glioma diagnosed pathologically were randomly divided into MRI group and MRI plus MRS group. The target volume was defined as the tumor enhanced area plus the surrounding area with a short T1 and a long T2 in the MRI group, while the tumor enha...

introduction: gamma knife is an instrument specially designed for treating brain disorders. in gamma knife, there are 201 narrow beams of cobalt-60 sources that intersect at an isocenter point to treat brain tumors. the tumor is placed at the isocenter and is treated by the emitted gamma rays. therefore, there is a high dose at this point and a low dose is delivered to the normal tissue surroun...

A 38-year-old man presented to a regional Western Australian hospital after being stabbed in his left eye with a knife. Computerized Tomography (CT) revealed a 7 cm knife blade within the globe extending along the skull base. After transfer to a tertiary hospital, a cerebral angiogram was performed, excluding significant cerebral vascular involvement. Through a multidisciplinary approach with t...

The Leksell Gamma Knife [Elekta Corp] uses helmets as collimators to produce four standard beam sizes. The nominal beam diameters are 18, 14, 8, and 4 mm. During computer treatment planning for gamma knife stereotactic radiosurgery, the size of the treated volume may differ from the standard beam sizes. To maintain conformality of the isodose curves to the treated volume, beam sizes may be supe...

The coexistence of moyamoya disease (MMD) with an arteriovenous malformation (AVM) is exceedingly rare. We report two cases of AVM associated with MMD. The first case was an incidental AVM diagnosed simultaneously with MMD. This AVM was managed expectantly after encephalo-duro-arterio-synangiosis (EDAS) as the main feeders stemmed from the internal carotid artery, which we believed would be obl...

The management of recurrent glioblastoma is highly challenging, and treatment outcomes remain uniformly poor. Glioblastoma is a highly infiltrative tumor, and complete surgical resection of all microscopic extensions cannot be achieved at the time of initial diagnosis, and hence local recurrence is observed in most patients. Gamma Knife radiosurgery has been used to treat these tumor recurrence...

INTRODUCTION Merkel cell carcinoma is a rare malignant cutaneous neoplasm that is locally invasive and frequently metastasizes to lymph nodes, liver, lungs, bone and brain. The incidence of Merkel cell carcinoma has increased in the past three decades. CASE PRESENTATION A 65-year-old Caucasian man presented with a sudden onset of severe headache and a three-month history of balance disturbanc...