Objectives: Researchers have focused their attention on balance in the elderly because there is a significant correlation between balance and fall. Therefore, it is very important to identify the factors that can affect elderly balance. The aim of this study was to investigate relation between sustained attention and balance in elderly. Methods: This cross sectional study was conducted in 20...

BACKGROUND Cognitive performance deteriorates during extended wakefulness and circadian phase misalignment, and some individuals are more affected than others. Whether performance is affected similarly across cognitive domains, or whether cognitive processes involving Executive Functions are more sensitive to sleep and circadian misalignment than Alertness and Sustained Attention, is a matter o...

BACKGROUND The aim of this study was to determine the rate of sustained virological response (SVR) and various factors associated with response rates in chronic hepatitis C infected patients treated with interferon alpha and ribavirin combination therapy. METHODS A retrospective review of patients data collected at this Centre from 2001 to 2007 was performed. Out of 731 consecutive patients 4...

BACKGROUND Although previous studies have examined the effects of acute hemodynamic pressure overload on proinflammatory cytokine gene expression, the effects of sustained hemodynamic overloading have not been examined. METHODS AND RESULTS Sustained hemodynamic pressure overloading was produced in mice by transverse constriction of the aorta. Proinflammatory cytokine and cytokine receptor gen...

Epidemiologic studies indicate that repetitive (cyclic) occupational activities lead to a cumulative trauma disorder (CTD), and the frequency or velocity of the movement is one of the risk factors. Experimental neurophysiological evidence to confirm the epidemiology is not available. The response of the multifidus muscles to cyclic loading in anterior lumbar flexion-extension was assessed to te...

A component of the event-related magnetic field (ERMF) response was observed in magnetoencephalographic signals recorded during the maintenance of information in visual short-term memory (VSTM). This sustained posterior contralateral magnetic (SPCM) field is likely the magnetic equivalent of the sustained posterior contralateral negativity (SPCN) found in electrophysiology. Magnetoencephalograp...

Static and dynamic work involving the arms and the legs was performed by 40 men seven weeks after myocardial infarction. Leg ergometry produced a significantly higher peak work load, systolic blood pressure (BPs), heart rate (HR), and HR X BPs X 10-2 product (DP) than did arm ergometry: 842 ± 178 vs 546 ± 135 kg-m/min, 176 ± 24 vs 154 ± 19 mm Hg and 256 ± 54 vs 219 ± 48 (SD). Peak heart rates w...

An electroencephalographic (EEG) marker of the limited contents of human visual short-term memory (VSTM) has previously been described. Termed contralateral delay activity, this consists of a sustained, posterior, negative potential that correlates with memory load and is greatest contralateral to the remembered hemifield. The current investigation replicates this finding and uses magnetoenceph...

High-dose nevirapine treatment has been reported to confer sustained antiretroviral effects, despite a rapid development of resistance. The use of this strategy was evaluated in 20 previously untreated human immunodeficiency virus type 1 (HIV-1) p24 antigenemic persons with CD4 cell counts between 100 and 500/mm3. Treatment consisted of 400 mg of nevirapine, after a 2-week lead-in dose of 200 m...

Sensory hair cell ribbon synapses respond to graded stimulation in a linear, indefatigable manner, requiring that vesicle trafficking to synapses be rapid and nonrate-limiting. Real-time monitoring of vesicle fusion identified two release components. The first was saturable with both release rate and magnitude varying linearly with Ca(2+), however the magnitude was too small to account for sust...