BACKGROUND The impact of co-morbid substance use in first-episode schizophrenia has not been fully explored. METHOD This naturalistic follow-up of a cohort of 152 people with first-episode schizophrenia examined substance use and clinical outcome in terms of symptoms and social and neuropsychological function. RESULTS Data were collected on 85 (56%) of the patient cohort after a median peri...

In vitro fertilization (IVF) is an important treatment for infertility, and in recent years, the delivery rate in IVF has increased markedly with the progress of reproductive medicine. However, chemical contaminants in IVF media have not been fully studied. A simple method using highperformance liquid chromatography coupled with tandem mass spectrometry was therefore investigated for quantitati...

BACKGROUND Attention-deficit hyperactivity disorder (ADHD) is a common and impairing neurodevelopmental disorder. The Cambridge Neuropsychological Test Automated Battery (CANTAB) is a computerized test battery with standardized procedures and solid psychometric properties targeting multiple neuropsychological functions. AIMS The aim of this study was to look at the effects of ADHD on cognitiv...

With urbanization, rising income and consumption, the production of waste increases. One most important directions in field sustainable development is design implementation monitoring management systems for collection removal. Smart (SWM) involves example analytics data from sensors on smart garbage bins (SGBs), trucks urban infrastructure; planning optimization truck routes; etc. The purpose t...

The Public Private Partnership (PPP) requires safe and conducive environment to safe guard the interest of the private partner against risk and that of consumers against likely abuse by the private partners. The private partners are not generally attracted towards PPP arrangement in solid waste management (SWM) services because of its complex operation and maintenance cost structure and difficu...

BACKGROUND A wide range of evidence supports the methylphenidate (MPH)-induced enhancement of prefrontal cortex (PFC) functioning and improvements in behavioral symptoms in patients with attention deficit hyperactivity disorder (ADHD). Although working memory (WM) has been hypothesized to be impaired in patients with ADHD, no pharmacological studies have examined visuospatial WM (VSWM) with nea...

Dosage for the galvanic stimulation for iontophoresis varies. Clinicians manipulate the duration or the amplitude of the current, but it is not known which is more effective. We compared the anesthetic effect of lidocaine HCL (2%) by manipulating the current parameters on 21 healthy volunteers (age: 21.2 ± 4.2, height 170.7 ± 10.2 cm, mass 82.1 ± 19.2 kg). Three conditions were administered in ...

Mutations of the fragile X mental retardation 1 (FMR1) gene are the genetic cause of fragile X syndrome (FXS). Large expansions of the CGG repeat (>200 repeats) consequently result in transcriptional silencing of the FMR1 gene and deficiency/absence of the FMR1 protein (FMRP). Carriers with a premutation allele (55-200 of CGG repeats) are often associated with mildly reduced levels of FMRP and/...

Onset of south west monsoon (SWM) over Kerala is associated with intense convection followed by heavy rainfall the west-coast India. The events are usually meso-scale convective systems embedded in large scale synoptic system Arabian Sea. Such deep and cumulus can have an important effect on dynamics energetics large-scale atmospheric systems, because magnitudes energy transformations changes p...

Climate projections have confirmed the need to adapt a changing climate, but been less beneficial in guiding how effectively adapt. The reason is uncertainty cascade, from assumptions about future emissions of greenhouse gases what that means for climate real decisions on local scale. Each steps process contains and these uncertainties various levels assessment accumulate. This cascade should b...