The predictive relevance of synovial fluid analysis and some other variables for the efficacy of intra-articular corticosteroid injections in 30 patients with rheumatoid arthritis and hydropsy in a knee joint was evaluated in a prospective study. At the onset of the study, the knee joints were aspirated and 30 mg triamcinolone hexacetonide injected intra-articularly. The circumferences and the ...

OBJECTIVE To optimise sample preparation of synovial fluid for Chlamydia trachomatis (CT) specific polymerase chain reaction (PCR). METHODS Serial dilutions of purified CT elementary bodies in synovial fluid were prepared. The synovial fluid pellet was processed by eight different methods of sample preparation. Then samples were analysed by CT specific PCR. The sensitivity of PCR was the basi...

Yersinia specific immune complexes were demonstrated in the synovial fluid of three patients out of 12 with yersinia triggered reactive arthritis. They were not detectable in the synovial fluid of any of the 16 control patients, including nine with reactive arthritis triggered by factors other than yersiniae. Platelet reactive IgG was detectable in the synovial fluid of eight out of the 12 pati...

Hyaluronic acid is the macromolecule which endows synovial fluid with its viscoelastic properties and it is often assumed these properties are important for the lubrication of the tissue surfaces in diarthrodial joints (Barnett, Davies, and MacConaill, 1961). The relationships, if any, that exist between the chemical and physical properties ofsynovial fluid and its lubricating ability, however,...

A 9 year old boy developed acute monoarthritis of the left knee concurrent with the appearance of a varicella zoster virus (VZV) rash. Repeated VZV DNA hybridisation of the cells within the synovial fluid and synovial membrane failed to show any evidence of intracellular virus. Virus was isolated from synovial fluid 24 hours after the start of clinical infection but not later. These findings su...

A 49 year old black man with scoliosis presented with bilateral shoulder swelling eventually shown to be due to neuropathic arthropathy related to underlying syringomyelia. The synovial fluid was highly inflammatory, but cultures from synovial fluid and synovial tissue were all sterile. Profuse fat droplets were noted and considered as a possible cause of the inflammation. This is an unusual pr...

1. Samples and extracts from synovial effusions were examined for the presence of fluorescent degradation products of free-radical oxidation (peroxidation). 2. Two classes of fluorescent compounds were identified and their fluorescence and physical properties are described. The fluorescence in the aqueous methanol phase of the extracts had the characteristics of conjugated Schiff bases. 3. Chan...

In the present investigation we have studied changes in the synovial fluid obtained from inflammatory and non-inflammatory joints, not only of lysosomal enzymes, but of five intracellular enzymes selected to represent different intracellular compartments. Although the study has not revealed a characteristic composition of the synovial fluid for any of the diseases studied, it has indicated that...

Objectives: To present a case of pancreatitis, panniculitis and polyarthritis syndome, including the full spectrum of the arthritis component. Methods: A case of PPP syndrome was examined, with a detailed review of the patient's synovial fluid aspirate including cell count, crystals, culture and a lipid analysis which was compared to a control patient. Results: The synovial fluid aspirate from ...

One case of arthritis complicating leukemia is described in which leukemic cells were identified in synovial fluid by light microscopy. Although arthritis is a well-known manifestation of leukemia with an incidence of 13.5%, the pathogenesis often is unclear, and the direct demonstration of leukemic cells in synovial fluid has been very uncommon. A 16 year-old male patient was admitted due to l...