TOPIC: Lung Cancer TYPE: Medical Student/Resident Case Reports INTRODUCTION: Synovial sarcomas (SS) are a rare group of malignancies, seen in 0.17 per 100,000 persons, accounting for 7% all soft tissue sarcomas. These malignant tumors most commonly present as tumor the extremities. While they have high propensity metastasis to bone and lung, primary intrathoracic malignancy is rare. We case pat...

Synovial sarcoma is a relatively common soft tissue malignancy that is characterized by a specific chromosomal t(X;18)(p11;q11) translocation. Transducin-like enhancer of split 1 (TLE1) has emerged as a useful marker for the diagnosis of synovial sarcoma. However, the diagnostic value of this antibody remains controversial. We investigated TLE1 expression in sixty-two fluorescence in situ hybri...

BACKGROUND Synovial sarcoma is a malignant neoplasm of soft tissues. It occurs mainly in the extremities and is closely related to tendons, tendon sheaths, and bursal structures. Primary synovial sarcoma of the pleura and lungs is extremely rare. CASE PRESENTATION We present the case of a 62-year-old man with a large synovial sarcoma of the left pleura. He presented with general fatigue and s...

Tumors of peripheral nerve are largely neuroectodermal in nature and derived from 2 elements of nerve, Schwann or perineurial cells. In contrast, mesenchymal tumors affecting peripheral nerve are rare and are derived mainly from epineurial connective tissue. The spectrum of the latter is broad and includes lipoma, vascular neoplasms, hematopoietic tumors, and even meningioma. Of malignant perip...

BACKGROUND Canine joint sarcomas, designated synovial sarcomas, are uncommon malignant mesenchymal neoplasms that occur in the large joints of the extremities of middle-aged, large-breed dogs. We report the diagnosis of an intrathoracic sarcoma with ultrastructural characteristics reminiscent of human synovial sarcoma in a dog. CASE PRESENTATION A 7-year-old female spayed Tibetan terrier cros...

Pulmonary sarcomas constitute only 0.1-0.5% of all primary lung malignancies. These tumors may derive from the lung parenchyma, bronchial tree or pulmonary arteries. The most important entity in the differential diagnosis is metastatic synovial sarcoma. A 76-years-old woman was admitted for investigation of a fever, productive cough, dyspnea, weight loss and left-sided chest pain which had been...