We present molecular dynamics results for the interaction between two solid elastic walls during pull-off for systems with and without octane (C(8)H(18)) lubricant. We used two types of substrate--flat and corrugated--and varied the lubricant coverage from approximately 1/8 to approximately 4 ML (monolayers) of octane. For the flat substrate without lubricant the maximum adhesion was found to b...

The revolution in industrialization throughout the world has boosted the utilization of machinery and shifted the muscle power to machines. The use of machines in various sectors has increased the demand of petroleum based lubricants. Lubricants act as an antifriction media, facilitating smoother working, reducing the risks of undesirable frequent failures and maintaining reliable machine opera...

Phorbol ester facilitates transmitter release at a variety of synapses, and the phorbol ester-induced synaptic potentiation (PESP) is a model for presynaptic facilitation. To address the mechanism underlying PESP, we have made paired whole-cell recordings from the giant presynaptic terminal, the calyx of Held, and its postsynaptic target in the medial nucleus of the trapezoid body in rat brains...

Novel routes for the preparation of 2-amino-4H-pyran-3-carbonitrile 9, amino-arylbenzoic acid ester derivatives 13a,b, 2-aminotetrahydro-4H-chromene-3-carbonitrile 18, 3-amino-4-cyanotetrahydronaphthalene-2-carboxylic acid ester 26 and 4-amino-3,5-dicyanophthalic acid ester derivatives 37a-c were developed. The synthetic methods utilize one-pot reactions of acetylene carboxylic acid esters, α,β...

DOCTORAL DISSERTATIONS A ato-D D 10 /2 13 Bioresorbable polymers are extensively studied materials for medical applications. In this thesis, novel bioresorbable polymers, hydrophobically-modified crosslinked poly(ester anhydride) networks, were developed and characterized with the aim of obtaining suitable matrices for drug release applications. In these poly(ester anhydride) networks were comb...

Sliding friction across a thin soft lubricant film typically occurs by stick-slip, the lubricant fully solidifying at stick, yielding and flowing at slip. The static friction force per unit area preceding slip is known from molecular dynamics (MD) simulations to decrease with increasing contact area. That makes the large-size fate of stick-slip unclear and unknown; its possible vanishing is imp...

We investigate the role of defects and disorder in a 2D-model lubricant interposed between two sliding substrates. Specifically, we consider localized defects (vacancies) and extended defects (grain boundaries) in the lubricant confined between two perfect rigid chains. This work verifies in particular when the perfect ”quantized” dynamical sliding regime identified in previous work [1, 2] is p...

Oil Chemical Research. USDA l-ARS-NCAUR. 1815 N. U;liuersity Street, Peoria, IL 61604, USA Accepted 8 October 1999 Compared to the lubricants made of petroleum, vegetable-based lubricants are much more biodegradable but inferior in many other technical characteristics. The basestock typically contributes to more than 80% of lubricant and must meet performance criteria in such aspects as cleanli...

Ko143 is a tetracyclic, synthetic analog of the fungal metabolite fumitremorgin C. potent and specific inhibitor membrane-bound efflux transporter ABCG2, it reverses ABCG2-mediated drug resistance in cancer cells. Here, we describe an improved synthesis that relies on highly selective, substrate-controlled reduction imine formed Bischler–Napieralski reaction with amide derived from 6-methoxy-l-...

Abstract—The traction behavior of lubricants with the linear pressure-viscosity response in EHL line contacts is investigated numerically for smooth as well as rough surfaces. The analysis involves the simultaneous solution of Reynolds, elasticity and energy equations along with the computation of lubricant properties and surface temperatures. The temperature modified Doolittle-Tait equations a...