the study aimed to assess the prevalence and associated risk factors of immediate-type hypersensitivity reactions (hrs) to drugs in workers. the data consisted of 1152 questionnaires obtained from adult men that consisted of questions on hrs induced by drugs. the prevalence of self-reported drug hrs was 3.6% for all reactions. hrs were most common to beta-lactam antibiotics (51.2%) followed by ...

Background: Psoriasis is a common disorder of the skin, immune system, and joints that is influenced by genetic and environmental factors. It can be aggravated or induced by drugs. Objectives: To identify the major drugs implicated in inducing or exacerbating psoriasis and to discuss their characteristics. Methods: We performed a PubMed literature search for reviews and case reports on drugs th...

Chronic diseases with evidence for systemic arterial hypertension are one of the main causes mortality in country. The treatment these is done through allopathic medicines and medicinal plants, their association increasingly frequent thus also increases risk interactions. A literature review was carried out on implications use plants interaction drugs used to control hypertension, based works p...

BACKGROUND/AIMS Lupus nephritis is an organ manifestation of systemic autoimmunity. Current treatment algorithms are still based on unselective immunosuppressive drugs. There is hope that highly selective biological drugs could be as or even more effective but less toxic. A profound understanding of the pathogenesis of lupus nephritis is necessary to identify the optimal molecular targets. ME...

Bullous pemphigoid is an autoimmune skin disease that results in formation of pruritic blisters. Most cases are treated with a combination systemic and topical corticosteroids as well other immunomodulatory drugs. Dupilumab fully human monoclonal antibody acts antagonist against IL4Ra traditionally used the treatment atopic dermatitis. We present 80-year-old man moderate to severe bullous succe...