The main purpose of the present investigation is the study of therapeutically effect of Zotepine in schizophrenia disease treatment. In first step, the molecular structure of the said compound is optimized using density functional theory (DFT) technique by B3LYP functional method at 6-311++G(d,p) level of theory. Then the electronic properties of the title molecule are calculated using frontier...

This paper proposes a model for describing lexical semantics within systemic-functional theory. Formal approaches to lexical semantics assume that words have meanings which exist independently from communication and are represented by means of (semi-) formal definitions. Functional approaches treat language as a tool for social interaction and, in the case of lexical semantics, assume that lexi...

Mesatua “storytelling” is a tradition that usually done by parents or grandparents in Bali. Storytelling uses Balinese folklore, which rich moral value. It an effort to preserve the language and culture develop cultural values. This study aims determine folklore’s transitivity social context applying systemic functional analysis theory. The result of showed elements consist process, participant...

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies and the formation of immune complexes that can damage multiple tissues, organs and systems. IL‐17 is a proinflammatory cytokine that plays an important role in several autoimmune diseases including SLE. The expression of IL‐17 is elevated in both SLE patients and in lupus‐prone m...

This work presents a theory to unify the two independent theoretical frameworks of Kohn-Sham (KS) density functional (DFT) and reduced matrix (RDMFT). The generalization KS orbitals hypercomplex number systems leads (HCKS) theory, which extends search space for in KS-DFT that is equivalent natural spin with fractional occupations RDMFT. Thereby, HCKS able capture multi-reference nature strong c...

Objective: To evaluate telomerase activity as a marker of lymphocyte proliferation in systemic lupus erythematosus (SLE). Methods: CD19+, CD4+, and CD8+ lymphocytes were isolated from the peripheral blood of nine patients with SLE and nine healthy controls by means of magnetic beadcoupled antibodies and tested for telomerase activity with the TRAP assay. Results: Telomerase activity was signifi...

Background Juvenile Systemic Lupus Erythematosus (SLE) is an autoimmune disease with variable clinical features. Neurologic and psychiatric symptoms are reported to occur in 10 to 80 percent of patients either prior to the diagnosis of systemic lupus erythematosus, or during the course of their illness. The neuropsychiatric manifestations of SLE are varied, and may be classified as primary neur...

Systemic lupus erythematosus (SLE) predominantly affects women of childbearing age, and the management of pregnant patients with SLE is challenging because pregnancy can aggravate SLE and vice versa. Furthermore, the drugs used to treat SLE can adversely affect the fetus. Accordingly, pregnancy should be planned in advance in women with lupus, and careful planning and treatment are required to ...

Systemic lupus erythematosus (SLE) is associated with inflammation of one or more of serous membranes resulting in pleural, peritoneal and pericardial effusion. Massive effusion had rarely been reported in patients with SLE and responded well to immunosuppressive therapy. We reported a case of SLE with recurrent massive ascites as the main presenting complaint with review of the available liter...

handed Z-DNA have been shown to be present in the sera of human patients with systemic lupus erythematosus (SLE). These antibodies are of two types. One type reacts with both denatured DNA and Z-DNA. The other type is specific for Z-DNA and remained in the serum after removal of the cross-reactive antibody by extensive absorption on a denatured DNA affinity column. The antibodies appear to be s...