The assembly of the Escherichia coli outer membrane (OM) is poorly understood. Although insight into fundamental cellular processes is often obtained from studying mutants, OM-defective mutants have not been very informative because they generally have nonspecific permeability defects. Here we show that toxic small molecules can be used in selections employing strains with permeability defects ...

1. Preliminaries Statistical methods are used to some extent in virtually all areas of science, technology, public affairs and private enterprise. The variety of applications makes any single unifying discussion difficult if not impossible. The present paper concentrates on the role of statistics in research in the natural and social sciences and the associated technologies. Our aim is to give ...

Can International Monetary Fund (IMF) lending improve natural resource governance in borrowing countries? While most IMF agreements mandate policy reforms exchange for financial support, compliance with these is mixed at best. The sector should be no exception. After all, windfalls enable short-term increases discretionary spending, and office-seeking politicians are often unwilling to forgo th...