In the ongoing series of Nova Interviews, Challenges Advisory Board member Alan C. Logan meets with thought leaders, scientists, scholars, healthcare professionals, artisans and visionaries concerned about health at scales persons, places, planet. this interview, Dr. Nalini M. Nadkarni, University Utah, responds to a set questions posed by for Challenges. For over forty years, Nadkarni has been...

In this paper, I examine design documents from three different ICT design and development projects. I argue that they present intersecting visions of sustainability entailing the wide-spread use of ICT, describe the properties of users compatible with such ICT, and provide ways of judging the users. In the design documents, the inhabitants are made individually responsible for living sustainabl...

Grief and hope are two conflicting emotions that a patient recently diagnosed with cancer has to master. The real challenge for gynecologic oncologists is how to reach out. Conventional wisdom states that offering patients focus and belief when combating cancer in their lives allows them to embrace hope with greater confidence, which minimizes their grief. Three pictorial models are presented: ...

In mammals, thousands of long non-protein-coding RNAs (ncRNAs) (>200 nt) have recently been described. However, the biological significance and function of the vast majority of these transcripts remain unclear. We have constructed a public repository, the Noncoding RNA Expression Database (NRED), which provides gene expression information for thousands of long ncRNAs in human and mouse. The dat...

Recent research in metaphor and analogy, as variously embodied in such systems as Sapper, LISA, Copycat and TableTop, speak to the importance of three principles of cross-domain mapping that have received limited attention in, what might be termed, the classical analogy literature. These principles are that: (i) high-level analogies arise out of nascent, lower-level analogies automatically reco...

An extended spectroscopic study on the left-through-left circularly polarized reflection spectra of a large number of beetles from the Australasian Scrabaeidae:Cetoniinae of the Lomaptera genus was undertaken. We have obtained a five-category spectral classification. The principal spectral features, which even within the genus range from blue to infrared, are related to structural chirality in ...

Peer-to-peer systems and applications are distributed systems without any centralized control. The core operation in most peer-to-peer systems is efficient location of data items. The current well-known peer-topeer systems like Napster and Gnutella have scalability problem in location of data items. To solve the scalability problem, some scalable peer-to-peer lookup services show up, such as CA...