The objective of this work has been the co-precipitation of the coating material Ethyl Cellulose (EC) and two natural extracts (IDOKI SCF Technologies), R1 and P1, using the Supercritical Antisolvent (SAS) precipitation technique with supercritical carbon dioxide (SC-CO2), in order to obtain active microparticles. EC is a hydrophobic material widely used for controlled delivery systems, sustain...

The present study was aimed towards the formulation and in vitro evaluation of orodispersible tablets by direct compression method using Risperidone as a model drug to enhance patient compliance. Orodispersible tablet of Risperidone was prepared by masking the bitter taste by cetyl alcohol using different ratios of drug with cetyl alcohol (2:1). Here crosspovidone and sodium starch glycolate in...

Antibiotics are not chemically stable in water based oral pharmaceutical suspensions. Anhydrous liquid antibiotic suspension for oral administration provides a product having good shelf life and taste characteristics relative to conventional liquid formulations. A ready to use oil based cefpodoxime proxetil preparation which can be stored at room temperature was prepared and evaluated for its o...

The paper describes an original method to represent chromi nance in color images and video This method can be combined with an arbitrary technique of luminance representation or compression The two chrominance components are represented by one scalar signal obtained using vector quantization The luminance is encoded entirely indepen dently from chrominance The scalar representation of chrominan...

Perceptual transparency requires local same-polarity X-junctions, which can also be generated by temporal integration under natural dynamic conditions. In this study, segmentation performance and target appearance were measured for a uniform gray target embedded in a random-dot frame presented with a temporally adjacent mask. Although static cues for both segmentation and transparency were unav...

We evaluated whether FLAVORx helped thirty Thai children take opened capsule, crushed tablets and liquid generic ARVs with more ease. All children had excellent adherence, evaluated by PACTG Standard International Questionnaire and interviewing, before and after one month of FLAVORx. Eighty percent took ARV with more ease and wish to continue FLAVORx. Strawberry was the most popular flavor.

A stable controlled release resinate-complex for the highly bitter taste famotidine (FAM) was developed to allow once-daily administration and improve patient compliance especially in pediatric and geriatric medicine. The drug-resinate complexes were prepared in different drug to resin (Amberlite IRP-69) ratios by weight (1:1, 1:2, 1:3, 1:4, 1:5 and 1:6). The optimized drug-resinate complex res...

In the case of chronic illnesses, fast-dissolving drug delivery systems were developed as an oral medication administration alternative to traditional dose forms. For masking taste unpleasant drugs and enhancing patient compliance, films are now recommended over tablets capsules. Fast dissolving consist a very thin strip that dissolves in less than one minute when placed on tongue. Customers ha...