The ORF75c tegument protein of murine gammaherpesvirus 68 (MHV68) promotes the degradation of the antiviral promyelocytic leukemia (PML) protein. Surprisingly, MHV68 expressing a degradation-deficient ORF75c replicated in cell culture and in mice similar to the wild-type virus. However, in cells infected with this mutant virus, PML formed novel track-like structures that are induced by ORF61, t...

A case of sporotrichosis in a woman presenting 63 cutaneous lesions distributed all over the tegument is related. The patient had both humoral (Immunoglobulins) and cellular (Lymphocytes subpopulations) immunity within normal limits, but was under treatment with steroid during a long time (Prednisone 10 mg daily for 2 years), due to a sciatic pain. In addition a review of the Brazilian literatu...

Members of the genus Habronema (Nematoda: Habronematidae) were preserved in 4 fixatives for examination with scanning electron microscopy (SEM). Tegumental features of the anterior and posterior extremities of these specimens were compared to evaluate the effect of the fixatives: modified Flemming's solution, glutaraldehyde (GA), Karnovsky's fixative and 70% ethanol. Fixatives were assessed on ...

VP22 is a major tegument protein of Equine herpesvirus type 1 (EHV-1) that is a conserved protein among alphaherpesviruses. However, the roles of VP22 differ among each virus, and the roles of EHV-1 VP22 are still unclear. Here, we constructed an EHV-1 VP22 deletion mutant and a revertant virus to clarify the role of VP22. We found that EHV-1 VP22 was required for efficient viral growth in cult...

Published Ahead of Print 28 January 2009. 2009, 83(7):3187. DOI: 10.1128/JVI.01579-08. J. Virol. Diefenbach and Anthony L. Cunningham Aggarwal, Bibing Tijono, Frazer J. Rixon, Russell J. Monica Miranda-Saksena, Ross A. Boadle, Anupriya Growth Cones of Human Fetal Axons Proteins and for Viral Exocytosis from Transport of Tegument and Envelope Secretory Vesicle Pathway for Anterograde Herpes Simp...

Annulotrematoides bryconi sp. n. is described and illustrated from specimens collected from gills of characiform fish, Brycon cephalus (Günther, 1869), in pisciculture ponds from Pirassununga, São Paulo, Brazil. Diagnostic characters of the new species are the tegument of trunk showing annulations, except on the cephalic regiona, and copulatory complex comprising sclerotized male copulatory org...

Paracoccidioidomycosis is an acute - to chronic systemic mycosis caused by fungi of the genus Paracoccidioides. Due to its frequent tegument clinical expression, paracoccidioidomycosis is an important disease for dermatologists, who must be up-to-date about it. This article focuses on recent epidemiological data and discusses the new insights coming from molecular studies, as well as those rela...

The present paper describes the ultrastructure of the surface topography, head organ, tegument, musculature, glandular system, primary alimentary tract and flame cells of the Chinese mainland strain of Schistosoma japonicum cercaria, as visualized with both scanning and transmission electron microscopes. The results not only illustrate the morphological features of the cercarial surface and its...