Giant cell arteritis is an inflammatory lesion of the large- and medium-sized arteries, usually involving the temporal arteries of older women. Rarely, the breast has been reported as the primary site of involvement. Patients usually present with breast masses that are tender or painful in most reported cases. The disease may be associated with constitutional symptoms that resemble polymyalgia ...

(2009). Increased angiotensin II type 1 receptor expression in temporal arteries from patients with giant cell arteritis. Ophthalmology, 116(5), 990-996. General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the...

Nine elderly patients presented with features of a multisystem disorder thought to be either a connective tissue disease of undefined type or disseminated malignancy. Associated features were a normochromic anaemia, raised erythrocyte sedimentation rate (ESR) (or plasma viscosity) and raised serum alkaline phosphatase levels. None had symptoms to suggest either giant cell arteritis or polymyalg...

Giant cell arteritis (GCA) or temporal arteritis or Horton’s disease is classified amongst the primary large-vessel vasculitides, according to the 2012 revision of the Chapel-Hill classifica‐ tion criteria. The disease develops almost exclusively in patients older than 50 years (preva‐ lence of 1 in 500 individuals in this age spectrum) and represents the most common vasculitis in Western count...

An 86-year-old woman presented with dysarthria and a painful tongue that looked dark and swollen and turned pale and offensive a few days later (Figure 1). Though the ESR was only 25 a strong clinical suspicion of giant cell arteritis led to an urgent referral for temporal artery biopsy. She was commenced on steroids whilst awaiting the biopsy, which was definitive. Owing to dysphagia she proce...

We report a rare case of association of temporal arteritis with recurrent central corneal ulcer. A 91-year-old male with a remote history of clinically diagnosed giant cell arteritis (GCA) and penetrating keratoplasty (PK) for corneal edema in 1990’s in the left eye presented with irritation and severe dry eye. He progressively developed central corneal ulcer regardless of treatment with aggres...

Large vessel vasculitides, such as Takayasu arteritis and giant cell arteritis, affect vital arteries and cause clinical complications by either luminal occlusion or vessel wall destruction. Inflammatory infiltrates, often with granulomatous arrangements, are distributed as a panarteritis throughout all of the artery's wall layers or cluster in the adventitia as a perivasculitis. Factors determ...