Hypertension and benign prostatic hyperplasia (BPH) are common disorders of aging men. As the world population is aging these two diseases are becoming a significant public health problem worldwide. Approximately 30% of men treated for BPH have coexisting hypertension. The α-Adrenergic Blockers: Prazosin, Terazosin and Doxazosin are established agents in the therapy of hypertension, and are als...

The role of intracellular cAMP and Ca(2+) in the excitation and adaptation of taste responses by HCl was investigated by direct measurement of intracellular pH (pH(i)) in polarized taste receptor cells (TRCs) and by chorda tympani (CT) nerve recordings. Stimulating the tongue with HCl concentrations between 1 and 30 mM caused a dose-dependent increase in CT responses that were insensitive to vo...

BACKGROUND The 32-item Hypomania Checklist (HCL-32), a questionnaire for screening bipolar disorders, has been utilised in several countries, but it unclear if the Chinese version of the HCL-32 is valid. METHODS Consecutive patients with bipolar disorders (BP, N = 300) and unipolar major depression (UP, N = 156) completed the Chinese version of the HCL-32. The subjects underwent a structured ...

OBJECTIVES This study was aimed to investigate effects of 2% minocycline-HCl paste root conditioning on periodontal surgery. MATERIALS AND METHODS In vitro, cementum slices affected by periodontitis were randomly conditioned with 2% minocycline-HCl paste, 2% minocycline-HCl liquid, and 0.9% saline. NIH3T3 cells were cultured and attached to the each slide, and the viability and proliferation ...

AIMS Glucosamine has been used safely to relieve osteoarthritis in humans, but the precise mechanism underlying its efficacy is still unclear. In this study, we investigated the direct effects of glucosamine and related compounds on mast cell mediated inflammation using cultured mast cells and an animal model. MAIN METHODS Dinitrophenyl (DNP)-IgE-sensitized rat basophilic leukemia RBL-2H3 cel...

A combination of 0.1% tetracaine HCl and 0.4% oxybuprocaine HCl is used when carrying out morphometrical corneal studies in vivo by means of ultrasound pachymetry. The aim of this was to determine the effect of a combination of 0.1% tetracaine HCl and 0.4% oxybuprocaine HCl anesthetic eye drops on central corneal thickness values. We carried out a prospective study involving 30 eyes of 30 healt...

DESCRIPTION Aloxi (palonosetron hydrochloride) is an antiemetic and antinauseant agent. It is a selective serotonin subtype 3 (5-HT3) receptor antagonist with a strong binding affinity for this receptor. Chemically, palonosetron hydrochloride is: (3aS)-2-[(S)-1-Azabicyclo [2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1oxo-1Hbenz[de]isoquinoline hydrochloride. The empirical formula is C19H24N2O.HCl, w...

An electroanalytical method has been introduced for highly sensitive determination of hydralazine hydrochloride (Hy-HCl) based on its oxidation at a glassy carbon electrode modified with multiwalled carbon nanotubes (MWCNT/GCE). Studies showed that the electrochemical oxidation of Hy-HCl was accompanied by adsorption and highly sensitive responses could be achieved by adsorptive stripping volta...

With the current emergence of green chemistry to keep the environment safe, attention is being shifted towards using plant extracts as corrosion inhibitors. The inhibitive performances of Talinum triangulare leaf extract and Musa sapientum peel extract on the ZA-27 in 1.0 M and 1.5 M hydrochloric acid solutions were studied for 18 days using mass loss measurement. The corrosion inhibition effic...

Context. Hydrogen chloride (HCl) and hydrogen fluoride (HF) are expected to be the main reservoirs of fluorine and chlorine over a wide range of conditions, wherever hydrogen is predominantly molecular. They are found to be strongly depleted in dense molecular clouds, suggesting freeze-out onto grains in such cold environments. We can then expect that HCl and HF were also the major carriers of ...