TOPIC: Critical Care TYPE: Medical Student/Resident Case Reports INTRODUCTION: Leflunomide (LEF) is a disease modifying antirheumatic drug. In this case report, we will highlight conditions which have been associated with LEF use and warrant immediate discontinuation early cholestyramine washout. CASE PRESENTATION: A 52 year old woman history of RA on prednisone LEF, stage 3 chronic kidney pres...

To conduct a systematic search to compare the efficacy and safety of disease-modifying therapies (DMTs) for treatment relapsing-remitting multiple sclerosis (RRMS). A literature PubMed was conducted identify phase III clinical trials in which DMTs RRMS were evaluated. The primary outcome this assessment annualized relapse rate (ARR). From with approximately 2-yr ARRs reported (n=13), outcomes a...