In the title racemic compound, C(26)H(32)N(2)O(3), an intra-molecular O-H⋯N hydrogen bond is formed between the phenolic OH group and the tertiary amine N atom. Another O-H⋯N hydrogen bond that is formed between the OH group and the pyridine N atom links the mol-ecules into a polymeric chain extending along the a axis. The structure is further stabilized by intramolecular and intermolecular C-H...

An electrochemically driven, nickel-catalyzed reductive coupling of N-hydroxyphthalimide esters with aryl halides is reported. The reaction proceeds under mild conditions in a divided electrochemical cell and employs a tertiary amine as the reductant. This decarboxylative C(sp3)-C(sp2) bond-forming transformation exhibits excellent substrate generality and functional group compatibility. An ope...

The direct α-heteroarylation of tertiary amines has been accomplished via photoredox catalysis to generate valuable benzylic amine pharmacophores. A variety of five-and six-membered chloroheteroarenes are shown to function as viable coupling partners for the α-arylation of a diverse range of cyclic and acyclic amines. Evidence is provided for a homolytic aromatic substitution mechanism, in whic...

A new coupling protocol has been developed that allows the union of vinyl sulfones with photoredox-generated α-amino radicals to provide allylic amines of broad diversity. Direct C-H vinylations of N-aryl tertiary amines, as well as decarboxylative vinylations of N-Boc α-amino acids, proceed in high yield and with excellent olefin geometry control. The utility of this new allyl amine forming re...

The present research provides data on the density (ρ), viscosity (η) and ability to absorb carbon dioxide of systems containing amine, molecular solvent (MS) choline chloride (ChCl), with investigation physical properties both neat amine/MS/ChCl mixtures their samples after complete CO2 saturation. effect mixture composition was studied by varying amine from primary (monoethanolamine, MEA) seco...

A streamlined approach to the tertiary amine-containing core of the calyciphylline A and daphnicyclidin A-type Daphniphyllum alkaloids is presented. A known carvone derivative is converted into the core structure in only four synthetic operations, and it is well poised for further elaboration. The key enabling methodology is a radical cyclization cascade beginning with addition of a secondary, ...

• Moisture increases CO 2 adsorption in the material modified with a tertiary amine. 13 ssNMR and DFT methods provided molecular insights into mechanisms. Selectivity remarkably amine moisture. DFT/cluster calculations confirmed water effect on adsorption. The of minor amounts CH 4 primary secondary amine-functionalised mesoporous silicas (APTES@SBA-15 DEAPTES@SBA15, respectively) was studied c...

to several advantages including superior mechanical properties, chemical and heat resistance, low shrinkage, high adhesivity and low toxicity [1]. However, one of the main drawbacks is the inherent fragility due to the high level of crosslinking in these materials. Because of this aspect, several methods to improve their toughness have been reported [2,3]. Our research group focused on improvin...

Amine resins are frequently studied to capture CO2 from industrial emission sources and air. Polyethylene imine (PEI) is a typical example showing relatively high uptake not too energy demanding desorption of CO2. For practical application, its oxidation stability great importance. In this DFT study, the ultimate two forms PEI, linear PEI (LPEI) branched (BPEI), investigated. First, order for a...

A new biological active hexapeptide of C-terminal of nocistatin, contains Glu-Gln-Lys-Gln-Leu-Gln sequence was synthesized according to solid phase peptide synthesis on the surface of 2-chloro tritylchloride resin and using fmoc-protected amino acids in the presence of TBTU (O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyl uranium tetrafluoroborate) as a coupling reagent. Then, amidation of the C-te...