BACKGROUND This report documents the authors' experience with 95 hypertelorism corrections performed since 1971. The authors note their findings regarding outcomes, preferred age at surgery, technique, and stability of results with growth. METHODS Patients were classified into three groups: midline clefts (with or without nasal anomalies, Tessier 0 to 14); paramedian clefts (symmetric or asym...

Although there is general agreement that L-glutamate can produce a depolarizing inward current to account for the hyperpolarizing (OFF) bipolar cell response, the conductance mechanism underlying the depolarizing (ON) response has been difficult to establish satisfactorily. To investigate the ionic bases of the center responses, we studied the whole-cell currents controlled by L-glutamate and i...

Introduction: Cartilaginous nasal septal agenesis is a rare finding. In fact, just one case has been reported to have congenital agenesis of all nasal cartilages in a 6-year-old child by Bakhshaee et al. The literature review shows another case that was reported by Ozek et al in Turkey, where they reported a case of total nasal agenesis that was associated with Tessier no. 30. We could not find...

Various authors have recently endorsed Harmonic Grammar (HG) as a replacement of Optimality Theory (OT). One argument for this move is based on computational considerations: OT looks prima facie like an exotic framework with no correspondent in Machine Learning, and the replacement with HG allows methods and results form Machine Learning to be imported within Computational Phonology; see for in...

Among the representations of congenital malformations in Moche ceramic art, cranio-facial clefts have been portrayed in pottery found in Moche burials. These pottery vessels were used as domestic items during lifetime and funerary offerings upon death. The aim of this study was to examine archeological evidence for representations of cranio-facial cleft malformations in Moche vessels. Pottery d...

IntroductIon There is evidence that the brain favors consumption of carbohydrates (CHO) rather than fats, this preference resulting in glycolysis-based energy metabolism domination. This metabolic mode, typical for consumers of the “Western diet” (Cordain et al., 2005; Seneff et al., 2011), is characterized by over-generation of reactive oxygen species and advanced glycation products both of wh...

ETNIER, J. L., R. J. CASELLI, E. M. REIMAN, G. E. ALEXANDER, B. A. SIBLEY, D. TESSIER, and E. C. MCLEMORE. Cognitive Performance in Older Women Relative to ApoE-?4 Genotype and Aerobic Fitness. Med. Sci. Sports Exerc., Vol. 39, No. 1, pp. 199–207, 2007. Introduction: Apolipoprotein E (ApoE) genotype and aerobic fitness are each associated with cognitive performance in older adults. However, the...

In 2012, the Annual General Meeting of the Clinical Investigator Trainee Association of Canada - Association des cliniciens-chercheurs en formation du Canada (CITAC - ACCFC) and the Canadian Society of Clinician Investigators (CSCI) was held 19-21 September in Ottawa. Several globally-renowned scientists, including 2012 Friesen International Prize recipient, Dr. Marc Tessier-Lavigne, the CSCI/R...