Downing, B.D., B.A. Bergamaschi, D.G. Evans and E. Boss. 2008. Estimating source-specific contributions of DOC into a drinking-water reservoir using optical profiling. Lake Reserv. Manage. 24:381–391. Understanding the sources of dissolved organic carbon (DOC) in drinking-water reservoirs is an important management issue because DOC may form disinfection by-products, interfere with disinfection...

As successful chemotherapy with the taxanes needs to reduce the toxic side effects against normal tissues and avoid the detrimental effects caused by intolerable solvents, drug delivery system using soluble polymeric micelles tends to be the focus. Docetaxel (Doc) has demonstrated extraordinary activities against a variety of solid tumors. However, the clinical efficacy is contrasted by its tox...

Dissolved organic carbon (DOC) export from soils can play a significant role in soil C cycling and in nutrient and pollutant transport. However, information about DOC losses from agricultural soils as influenced by management practices is scarce. We compared the effects of mineral fertilizer (MF) and liquid hog manure (LHM) applications on the concentration and molecular size of DOC released in...

Experimental techniques are now available which can probe the intricacies of carbohydrate structures, equilibria and dynamics. The development of theoretical tools has not kept pace with this progress; the reliance on hard sphere models and orientational averaging is unlikely to reveal the true nature of the phenomena involved. Computer simulation of PHCs in solution may, in the hands of expert...

materials and methods liposomes were prepared by thin film method using soya lecithin and cholesterol. physicochemical characteristics of the liposomes such as, particle size, drug encapsulation efficiency were determined. also, drug release and in vitro skin permeability through rat skin were evaluated using franz diffusion cells. results the results showed that the maximum drug encapsulation ...

Fluxes of dissolved organic carbon (DOC) from marine sediments represent a poorly constrained component of the oceanic carbon cycle that may affect the concentration and composition of DOC in the ocean. Here we report the first in situ measurements of DOC fluxes from continental margin sediments (water depths ranging from 95 to 3,700 m), and compare these fluxes with measured benthic fluxes fro...

Resource availability constrains the life history strategies available to organisms and may thereby limit population growth rates and productivity. We used this conceptual framework to explore the mechanisms driving recently reported negative relationships between fish productivity and dissolved organic carbon (DOC) concentrations in lakes. We studied populations of bluegill (Lepomis macrochiru...

In the past decade, significant increases in surface water dissolved organic carbon (DOC) have been reported for large aquatic ecosystems of the Northern Hemisphere and have been attributed variously to global warming, altered hydrologic conditions, and atmospheric deposition, among other factors. We analyzed a 25-yr DOC record (1988-2012) available for a forested headwater stream in the United...

Docetaxel (DOC) and 5-fluorouracil (5-FU) are important anticancer agents widely used in the treatment of a variety of cancers including oral squamous cell carcinoma (OSCC). The purpose of this study was to determine the antitumor efficacy of the sequential administration of DOC and 5-FU against OSCC cells (B88 and CAL27 cells) in vitro and in vivo. In in vitro growth inhibition assays, sequent...