Purpose: To compare the efficacy of computer-aided dosing using Coagclinic (a web-based software) with physician dosing in patients receiving warfarin for various cardiac indications. Met hods: In order to calculate the effectiveness of physician managed anticoagulation dosing, we calculated the “percentage of time international normalized ratio, INR, was in the therapeutic range" (TTR) for a r...

Therapeutic communities (TCs) for addictions are drug-free environments in which people with addictive problems live together in an organized and structured way to promote change toward recovery and reinsertion in society. Despite a long research tradition in TCs, the evidence base for the effectiveness of TCs is limited according to available reviews. Since most of these studies applied a sele...

Clinicians have been working out ways to incorporate buprenorphine into their treatment models. Representatives of three addiction treatment programs - a Veterans Affairs methadone clinic, a group of outpatient mental health centers, and a nationwide organization of therapeutic communities - talk about their plans and experiences.

The inability of government, communities and churches to deal with complex HIV and AIDS challenges may foster pathological psychosocial and systemic dysfunctionalities. The reframing of pathological and disempowering pastoral therapeutic and health promotion praxes are sought. The objective was to construct a new pastoral and social therapeutic methodology. It should develop in line with health...

Outpatient therapeutic programme (OTP) is one of the approaches community-based management acute malnutrition (CMAM), which includes community engagement and mobilization for outpatient uncomplicated severe (SAM) children 6–59 months with good appetite, by providing them home-based treatment as Ready-to-use Therapeutic Food (RUTF) routine medical treatment. Around 85-90% SAM are successfully tr...

BACKGROUND Pharmacy benefit managers (PBMs) play a major role in administering prescription drug benefit programs for health plans and employers. PBMs have often encouraged the use of self-owned mail-order pharmacy services with the promise to plan sponsors of lower prescription drug costs compared with those of the community pharmacy network. Some plan sponsors have requested a higher degree o...

Missing data is a pervasive problem in longitudinal treatment research studies. Missing data due to study non-completion complicate the task of drawing conclusions about the effect of a treatment or policy on a measure of interest (e.g., a process measure or outcome). Biased estimates of change over time in a measure could result if attrition is related to the constructs that are being measured...

background: proteolytic enzymes have an important role in variety of physiological and pathological functions. they have been used in therapeutic and pharmaceutical applications. characterizations of extracellular proteases from various strains of s. marcescens indicate that most strains produce a very similar major metalloprotease. this metalloprotease (serrapeptidase, serrapeptase) is an impo...

background and aims: crocus sativus is of medicinal plants possessing many beneficial effects in treatment of various disorders. this study aimed to overview the therapeutic effects of crocus sativus on the basis of reviews and systematic reviews. methods: computerized search of review articles was performed using pubmed, google scholar, scopus and web of science, medline database from 1996 to ...

background: cd52 is a small glycoprotein with a gpi anchor at its c-terminus. cd52 is expressed by normal and malignant t and b lymphocytes and monocytes. there are detectable amounts of soluble cd52 in plasma of patients with cll and could be used as a tumor marker. although the biological function of cd52 is unknown but it seems that cd52 may be involved in migration and activation of t-cells...