Alzheimer’s disease (AD) is known for some well-characterized pathological changes including the extracellular accumulation of amyloid plaques, intra-neuronal presence of neurofibrillary tangles, glial hypertrophy and neuronal death [1-3]. Paradoxically, myelin pathology in human AD has not been widely studied, even though it has been more than a century since Alois Alzheimer described myelin d...

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive loss of cognitive function and subsequent death. Since the first case of this disease was diagnosed one century ago, much effort has been dedicated to find a cure. However, even though progress has been made in the knowledge of the pathogenesis of this disease, an effective treatment has not been found...

The article deals with artifacts found in the Iron Age kurgans over Trans-Uralian and West Siberian forest-steppe, which might be referencing for chronology of Sargat culture late complexes emerging within area under study. Our emphasis is placed on analyses some belt strap fittings. Meanwhile novelty undertaken research viewed less general discussion chronological aspects but it brings to ligh...

Iran has a rich civilization and a long history during which medical science flourished at specific periods. For instance, medicine blossomed in Sassanids era (226 - 652 AD). One of the most remarkable cultural and scientific centers of Sassanids era was the city of Gondishapur located in the south-west Iran in Shah-Abad near Susa in Khuzestan Province. The city was rebuilt in the third century...

The evolution of the hospital is traced from its onset in ancient Mesopotamia towards the end of the 2nd millennium to the end of the Middle Ages. Reference is made to institutionalised health care facilities in India as early as the 5th century BC, and with the spread of Buddhism to the east, to nursing facilities, the nature and function of which are not known to us, in Sri Lanka, China and S...

results bahaodowle razi, a persian physician from the 15th century anno domini (ad), reported two epidemics in harat and one in rey (inold persia) for the first time, one century before baillou. he named it as sorfe-ie-am (meaning public cough). those occurred during his lifetime. explaining about his observations and experiences about this epidemic, bahaodowle razi elaborated on prognosis, sym...

conclusions higher prevalence of t. gondii in patients with ad compared to controls showed the possible impact of this parasite in ad, which may exacerbate symptoms, and this requires special attention of specialists and patient families. results the overall prevalence of t. gondii infection in patients with ad and the control group, using elisa assay, was obtained as 66.6% (58/87) and 56.32% (...

concerning the article on ”cataract surgery in albucasis manuscript” pages 75-76 which is published in this issue of iranian journal of ophthalmology (irjo) a few points took my attention worth mentioning.     the science of ophthalmology and cataract surgery was developed 6,000 years ago, not in egypt but at mesopotamian region. the babylonians mastered this science 2,000 years before the glor...

2012 ACKNOWLEDGMENTS I would like to thank all people which have made this work possible. I express my sincere gratitude to my supervisor, Professor Militon Frent¸iu, for his help during these years. I also thank Professor Horia F. Pop for research opportunities offered and valuable ideas. The passion for research, encouragements and many ideas came from my coleague Andreea Vescan to whom I am ...