نتایج جستجو برای: thrombocytopenic purpura
تعداد نتایج: 13583 فیلتر نتایج به سال:
Cannabis used as both for medicine well recreational purposes. Extensive use is associated with many documented central nervous system and hepatic manifestation. How-ever only few cases are reported in literature cardiac hematological Our case report one of its kinds where our patient presents thrombotic thrombocytopenic purpura atrial fibrillation he required extensive treatment including plas...
BACKGROUND Treatment of chronic refractory idiopathic thrombocytopenic purpura is a dilemma because many patients have minimal symptoms, response to treatment is uncertain, and treatments may have serious adverse effects. PURPOSE To determine the effectiveness of treatments for adult patients with idiopathic thrombocytopenic purpura who have not responded to splenectomy. DATA SOURCES Englis...
BACKGROUND Von Willebrand factor (VWF) multimer size is controlled through continuous proteolysis by ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type I motif, member 13). This prevents spontaneous platelet agglutination and microvascular obstructions. ADAMTS13 deficiency is associated with thrombotic thrombocytopenic purpura, in which life-threatening episodes of microan...
BACKGROUND The role of high-dose dexamethasone in the treatment of immune thrombocytopenic purpura in adults is controversial. We assessed the effectiveness of high-dose dexamethasone as initial treatment in a series of consecutive adults with immune thrombocytopenic purpura. METHODS Consecutive patients with newly diagnosed immune thrombocytopenic purpura and a platelet count of less than 20...
BACKGROUND Acquired thrombotic thrombocytopenic purpura is still associated with a 10-20% death rate. It has still not been possible to clearly identify early prognostic factors of death. This study involved thrombotic thrombocytopenic purpura patients with acquired severe (<10% of normal activity) ADAMTS13 deficiency and aimed to identify prognostic factors associated with 30-day death. DESI...
OBJECTIVE To determine the outcome of splenectomy done in adult patients of Idiopathic Thrombocytopenic Purpura over a period of 10 years and, secondarily, to determine the predictors of complete response to therapy. METHODS The retrospective review comprised of adult patients over 14 years of age who underwent open or laparoscopic splenectomy for Idiopathic Thrombocytopenic Purpura at Aga Kh...
Ten cases of isoimmune neonatal thrombocytopenic purpura (4 pairs of siblings and 2 singletons) are described. The condition was diagnosed by excluding other causes of thrombocytopenia , and in 8 cases it was confirmed by detecting antiplatelet antibodies in the mother. Perhaps steroids should be given to affected infants as soon as the condition is diagnosed in order to stabilise the capillary...
A systematic review of the efficacy and safety Jianpi Yiqi combined with glucocorticoids in treatment immune thrombocytopenic purpura. Randomized controlled trial therapy glucocorticoid for purpura was retrieved without any restrictions on blindness language. that met inclusion criteria were screened, Revman5.3 software used meta-analysis. total 27 articles included 1716 cases. The results meta...
Background: Plasma exchange is first-line therapy for patients with thrombotic thrombocytopenic purpura (TTP). Splenectomy is often indicated for patients with relapsing or refractory disease. Concerns exist about its efficacy and safety in these patients. We describe a series of patients whose TTP was treated with laparoscopic splenectomy. We also reviewed the literature in order to describe t...
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