background: infections attributed to helicobacter pylori ( h. pylori ) involve almost half of the world's population. one of the effects is auto-antibody induction and cross-reaction with numerous proteins in the body. as a result of its widespread prevalence and importance, this study evaluates the associations between h. pylori and thyroid auto-antibodies. materials and methods: this study en...

Here we report three cases of hyperthyroid Graves' disease that occurred after partial thyroidectomy for papillary carcinoma. In Case 1, the patient first developed hyperthyroidism 2 years after resection of left thyroid lobe, was treated for 2 years with antithyroid drug which was then discontinued, and relapsed with periodic paralysis after 8 years of remission. In Case 2, a hyperfunctioning ...

BACKGROUND Autoimmune comorbidities and circulating autoantibodies have been observed in vitiligo patients, but differences in rate are present according to countries in which the studies were performed, perhaps owing to ethnic diversities or different trigger factors. OBJECTIVE To estimate the prevalence of circulating autoantibodies and overt autoimmune diseases in a fairly large sample of ...

Injection of human thyroglobulin solution into rabbits gave rise to a transient 19S antibody response which could however be maintained by repeated administration of antigen. When the antigen was coated onto acrylic resin particles, the titre of 19S antibodies was increased nearly 20-fold whereas 7S antibody levels were unchanged. This selective enhancement of 19S antibody synthesis by particul...

Type 1 diabetes mellitus (T1D), autoimmune thyroid disease, and autoimmune gastritis often occur together forming the so-called autoimmune polyendocrine syndrome type 3 (APS3). We here report a clinical case of a 74-year-old woman who presented for the first time with severe hyperglycemia and ketoacidosis diagnosed as T1D. Further clinical investigations revealed concomitant severe hypothyroidi...

Several studies have appeared in the past 25 years (l-5) concerning the physicochemical properties of thyroglobulin, the protein precursor of the thyroid hormone thyroxine. Most of this work has utilized hog thyroid gland as a source of material. The various investigations are in rather good agreement in obtaining a molecular weight for thyroglobulin close to -$ million. Moreover, this form of ...

Gostimir MIKAČ Faculty of Medicine Save Mrkalja 22 78000 Banja Luka Republic of Srpska Bosnia and Herzegovina [email protected] SUMMARY Introduction Thyroglobulin is composed glycoprotein, and it is synthesized by follicular cells of the thyroid gland. Treatment of differentiated thyroid carcinomas involves total thyroidectomy followed by radioiodine ablation of a potential remaining tissue. The m...

Abstract Background Glucocorticoid treatment is used in children with Graves’ disease (GD) only cases of exophthalmos. The purpose this study was to observe the effects glucocorticoid pulse therapy on thyroid function and antibodies GD. Methods Twenty who were treated by intravenous methylprednisolone (MPT) followed oral prednisolone administration antithyroid drugs included group. alone contro...

The current study is designed to investigate the histological and immunohistochemical characteristics of thyroid gland in adult male Sciurus anamalus. This found that Caucasian squirrel located neck area, below larynx, on both sides trachea. It has two lobes (right left) with cylindrical shape. studies revealed surrounded by a capsule which consists connective tissue forming layers are outer la...