In the last decade, discoveries in molecular biology field have allowed new insight into the genes involved in the development of AITD. At least six susceptibility genes whose variants have been associated with AITD were identified: HLA-DR, CD40, CTLA-4, PTPN22, thyroglobulin (Tg), and thyroid stimulating hormone (TSH) receptor. Genetic susceptibility accounts for 70 % risk for disease that, on...

Thyroid nodules are a common clinical problem and with the growing use of diagnostic imaging, the number of thyroid nodules identified and undergoing further diagnostic evaluation by fine-needle aspiration biopsy (FNA) is steadily growing. Only 5 % of all thyroid nodules harbour malignancy and thyroid cancer constitutes only 1 % of all epithelial malignancies worldwide and represents 95 % of al...

Assess the knowledge regarding prevention of complications thyroid disorders among women attending endocrine OPD, MGM hospital, Warangal, Telangana

The relationship between thyroid dysfunction and breast cancer (BC) is debated. To clarify this controversial issue, a prospective study on thyroid function in BC was performed. The prevalence of thyroid disease was examined in 102 consecutive BC patients with ductal infiltrating carcinoma after surgery and before starting any chemohormonal or x-ray therapy and in 100 age-matched control health...

• Although, it is assumed that digitalis glycosides are relatively ineffective in heart failure and atrial fibrillation associated with disorders of thyroid gland function," there is little experimental work to support this belief. Frye and Braunwald observed that administration of triiodothyronine to euthyroid and hypothyroid patients with chronic atrial fibrillation increased the dose of card...

Background: Anti-thyroid peroxidase antibody (anti-TPO antibody) is a member of thyroid autoantibodies which are important in inducing and also diagnosing autoimmune thyroid diseases. Thyroid autoimmunity can cause several forms of thyroiditis and abnormal thyroid functions, ranging from hypothyroidism to hyperthyroidism. Objective: To evaluate the relationship between serum levels of anti-TPO ...

Iodine is a trace element essential for synthesis of the thyroid hormones, triiodothyronine and thyroxine. These hormones play a vital role in the early growth and development stages of most organs, especially the brain. The World Health Organization (WHO) has declared that, after famine, iodine deficiency is the most avoidable cause of cerebral lesions including different degrees of mental ret...

Iodine is an essential trace element whose only confirmed function concerns the formation of thyroid hormones. Our knowledge of the disorders caused by deficiencies in the dietary supply of many trace elements has markedly increased only during the last decade. Iodine is one exception to this rule. The role played by iodine deficiency in the etiology of disorders of the thyroid gland and in par...

AIM To present the clinical and laboratory features of patients with dermatologic disorders associated with thyroid diseases, diagnostic criteria, type of administered treatment and its effectiveness. MATERIAL AND METHODS This study is a retrospective study based on the medical records of patients with thyroid diseases admitted to the Dermato venereology Clinic of the Iasi "Sf. Spiridon" Univ...