Thyroid lobectomy or hemithyroidectomy is considered an adequate treatment for several thyroid diseases such as large benign nodules, follicular neoplasm, and some suspected malignancies. Thyroid lobectomy theoretically preserves sufficient functioning native thyroid tissue for patients to keep euthyroid status postoperatively without the need for thyroid hormone replacement. Still, it is known...

We have recently found an increased expression of amyloid precursor protein (APP) in cold thyroid nodules that are difficult to classify as a truly benign thyroid neoplasm or a lesion with the potential for further dedifferentiation. Since differences in APP activity have been found in other human cancers, we asked whether thyroid carcinogenesis might be associated with an altered APP expressio...

Background: Thyroid nodules are abnormal growths of thyroid tissue which commonly arise within an otherwise normal gland. They may be hyperplasia or a neoplasm, but only small percentage the latter cancers. Objectives: To improve management patients and to reduce cost-effectiveness by decreasing number unnecessary fine needle aspiration cytology (FNAC). Patients Methods: This study was conducte...

Developed for scarless neck surgery and conceived as a modification of the axillo-bilateral breast approach, bilateral axillo-breast approach (BABA) is method extracervical endoscopic thyroidectomy that currently one most popular techniques in world. Since da Vinci robotic system was used to overcome many technical disadvantages BABA thyroidectomy, indications thyroidectomy(BABA-RT) could be la...

Introduction: Thyroid disease is the worlds second most frequent endocrine condition after diabetes. Nearly 300 million individuals worldwide are affected. Moreover, approximately 60% of people with thyroid completely unaware their medical condition. might have been an underlying leading to death, even if its not primary cause death. Methods: This type research descriptive a retrospective study...

Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was introduced to cover a group of noninvasive encapsulated follicular-patterned thyroid lesions with very low malignant behavior. This nomination may have a great impact on the incidence of thyroid malignancy and the practice for endocrine pathologists. To demonstrate the proportion of the thyroid follicular ...

We investigated if the use of two tumor markers, galectin-3 and CD44v6, could improve diagnostic accuracy of thyroid fine needle aspiration biopsy (FNAB) in cytologically indeterminate lesions (CIL). 351 patients with CIL [cellular follicular lesion/suspicious follicular neoplasm/suspicious Hürthle cell neoplasm (CFL/sFN/sHCN), Hürthle cell neoplasm (HCN), and follicular neoplasm (FN)] and surg...

In Japan, fine-needle aspiration (FNA) cytology is the most important diagnostic modality for triaging patients with thyroid nodules. A clinician (endocrinologist, endocrine surgeon, or head and neck surgeon) generally performs FNA cytology at the outpatient clinic, and ultrasound (US)-guided FNA is widespread because US is extremely common and most clinicians are familiar with it. Although alm...

Objective: The objectives were to evaluate fine needle aspiration cytology results of 39 pediatric patients, and the pathologies that cause childhood thyroid nodules, and to review the literature on the subject. Material and Method: Thyroid fine needle aspiration cytology results of 39 pediatric patients were retrospectively reviewed. Associated diseases, thyroid functions, anti-thyroid antibod...

Merkel cell carcinoma is an extremely rare neuroendocrine neoplasm of the external auditory canal (EAC) skin, which requires wide excision and adjuvant radiation due to a high recurrence rate. In this report, we describe case arising from EAC was successfully treated with endoscopic excision. A 32-years-old female patient history papillary thyroid cancer diagnosed tumor incidentally. There eryt...