Thyroid tissues in coho salmon (Oncorhynchus kisutch) goiters showed marked regional variation in structure and ultrastructure. For the most part the follicles were small, were composed of tall epithelial cells, and con tained little or no colloid material. The follicle epithelial cells were essentially similar in fine structure to hyperac tive thyroids in mammals and one type of follicle in co...

Thyroid tissues in coho salmon (Oncorhynchus kisutch) goiters showed marked regional variation in structure and ultrastructure. For the most part the follicles were small, were composed of tall epithelial cells, and contained little or no colloid material. The follicle epithelial cells were essentially similar in fine structure to hyperactive thyroids in mammals and one type of follicle in cong...

PURPOSE To study quantitatively C cells in the thyroids of non-isogenic rats to determine the possible effects of pinealectomy on the number of these cells, and consequently on the synthesis and secretion of calcitonin. METHODS Twenty male rats of an outbred strain (200-300 g) were used in the present study. One group of 10 animals was pinealectomized 50 days prior to sacrifice. Thyroid tissu...

Application of molecular techniques has greatly contributed to functional morphology in the field of thyroid pathology. These techniques can demonstrate expressions of the specific genes or proteins for thyroid cells including follicular cells and C cells. Therefore, they facilitate defining the spectrum of thyroid tumors. Recent studies showed that thyroid transcription factor-1 (TTF-1) is ide...

Four experiments involving 163 pigs were conducted to determine the effects of iodine level in a corn-soybean meal diet on body weight gain, feed required per unit gain and thyroid status. Pigs fed the basal diet (.055 ppm iodine) with no supplemental iodine had lower plasma protein-bound-iodine levels, hypertrophied thyroids and trapped a greater amount of a 5 /~c dose of radioiodine (l st I) ...

MONGOLISM, a common clinical entity (1) of unknown etiology is believed to result from deceleration of normal growth during the fetal period (2). A possible relationship between abnormalities in development and function of the thyroid gland and the fetal growth process in mongolism is suggested by anatomic evidence of pathologic alterations in the thyroids of mongoloid children (1, 3), and the ...

Among 436 959 live infants born between 1970 and 1975 in Denmark were 72 (49 girls and 23 boys) who developed primary hypothyroidism, giving an incidence of 1 in 6064 live births. In the oldest group (6 to 8 years of age) the incidence was 1 in 5100. The age at diagnosis ranged from 1 week to 5 years 4 months; 10% were diagnosed within the first month, 40% within the first 3 months, and 70% wit...