AIMS To investigate the relationship between diabetes and inflammation and the potentially synergistic relationship between hyperglycaemia and inflammation on clinical outcomes in non ST-elevation ACS. METHODS AND RESULTS The principal analysis was conducted in 2200 patients in OPUS-TIMI 16 with C-reactive protein data available and then validated in the invasive arm of TACTICS-TIMI 18 (n = 9...

BACKGROUND To assess the added value of the 6 minute walk test distance (6MWTD) in the risk-stratification methods for patients with ST -segment elevation myocardial infarction (STEMI) treated with fibrinolysis. METHODOLOGY/PRINCIPAL FINDINGS This is a prospective cohort study of one hundred consecutive patients with STEMI, who had received fibrinolysis, at Assuit University Hospital. All pat...

Four risk scores for stratifying patients with chest pain presenting to emergency departments (EDs) (namely Thrombolysis in myocardial infarction [TIMI], Global registry for acute coronary events [GRACE], Banach and HEART) have been developed in Western settings but have never been compared and validated in Chinese patients. We aimed to find out to the number of MACE within 7 days, 30 days, and...

OBJECTIVES We hypothesized that impaired renal function would also be associated with poorer clinical outcomes among patients with ST-segment elevation myocardial infarction (STEMI) treated with fibrinolysis. BACKGROUND Previous studies have demonstrated that impaired renal function is associated with poorer clinical outcomes in the setting of unstable angina and non-STEMI and after percutane...

Objective: Chest pain is amongst the most frequently occurring symptoms in patients presenting to emergency department (ED). Accurate and fast risk stratification paramount for identification of with immediate acute coronary syndrome (ACS). The present study has compared different scoring systems like HEART (History, ECG, Age, Risk factors, Troponin), Thrombolysis Myocardial Infarction (TIMI), ...

BACKGROUND Although improved epicardial blood flow (as assessed with either TIMI flow grades or TIMI frame count) has been related to reduced mortality after administration of thrombolytic drugs, the relationship of myocardial perfusion (as assessed on the coronary arteriogram) to mortality has not been examined. METHODS AND RESULTS A new, simple angiographic method, the TIMI myocardial perfu...

OBJECTIVES Cardiac multidetector computed tomography (CMCT) has potential to be used as a screening test for patients with acute chest pain, but several tools are already used to risk-stratify this population. Risk models exist that stratify need for intensive care (Goldman), short-term prognosis (Thrombolysis in Myocardial Infarction, TIMI), and 1-year events (Sanchis). We applied these cardio...

Objectives: This study was conducted to compare the predictive power of Shock Index (SI), TIMI Risk (TRI), LASH Score, and ACEF Score for prediction in-hospital mortality in a contemporary cohort ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) at tertiary care cardiac center developing country.
 Methodology: Consecutiv...

Abstract Background and aim Standard single antiplatelet regimen (SAPT) is currently recommended before invasive risk stratification in non-ST elevation acute coronary syndromes (NSTE-ACS). However, there are subsets whom dual therapy (DAPT) may be more protective according to the anatomy revascularization strategy. We aimed identify pre-procedural predictors of artery complexity that helpful s...