The present study aimed to investigate whether bone marrow-derived mesenchymal stem cell (BMSC) sheets combined with titanium implants enhanced implant osseointegration in an ovariectomized (OVX) rat model of osteoporosis. Sprague-Dawley rats were randomly assigned into a test group and control group. Allogenic BMSCs were collected from the rats, cultured and stored via cryopreservation. At 6 m...

With millions of new dental and orthopedic implants inserted annually, periprosthetic osteolysis becomes a major concern. In dentistry, peri-implantitis management includes cleaning using ultrasonic scaling. We examined whether ultrasonic scaling releases titanium particles and induces inflammation and osteolysis. Titanium discs with machined, sandblasted/acid-etched and sandblasted surfaces we...

INTRODUCTION In the 1960’s Brånemark successfully pioneered the use of transcutaneous implants in the dental field, however subsequent attempts to translate these findings into a solution for amputees have been beset with complications. Infection is the primary failure modality because the skin breach provides a route for pathogens to enter the body. Intraosseous transcutaneous amputation prost...

Current trends in clinical dental implant therapy include use of endosseous dental implant surfaces embellished with nanoscale topographies. The goal of this review is to consider the role of nanoscale topographic modification of titanium substrates for the purpose of improving osseointegration. Nanotechnology offers engineers and biologists new ways of interacting with relevant biological proc...

Although titanium/hydroxyapatite composite is an attractive material for dental implants, it would be more useful if it could be produced as a functionally graded material (FGM). In this paper, microstructure and microhardness of a five-layer titanium/hydroxyapatite functionally graded material has been investigated. First, titanium and hydroxyapatite (HA) powders were mixed with the Ti to HA v...

Pure titanium or titanium alloys, and to a lesser extent, zirconium, are metals that are often used in direct contact with host tissues. These metallic biomaterials are highly reactive, and on exposure to fluid media or air, quickly develop a layer of titanium dioxide (TiO2) or zirconium dioxide (ZrO2). This layer of dioxide forms a boundary at the interface between the biological medium and th...

statement of the problem replacement of missing or lost teeth with dental prostheses supported by dental implants has been accepted and received positive evaluations from patients who have undergone implant treatment. purpose the aim of this study was to evaluate the level of patient knowledge about dental implants among a selected sample of dental patients in tabriz, iran materials and methods...

Long-term stability of orthopaedic and dental implants depends on the integration of the artificial material into the surrounding bone tissue. The physical and chemical properties of implants, including those made of metals such as titanium, are thought to influence osseointegration. Despite the known importance of this interface, little is known about the factors that promote its formation. In...

DNA-based coatings possess beneficial properties useful for medical and dental implants. The present study evaluated the potential in vivo bioactivity of DNA-based coatings, either or not pretreated in simulated body fluid (SBF). DNA-based coatings were generated on titanium cylinders using layer-by-layer deposition, with bis-ureido-surfactant as the cationic component and DNA as the anionic co...

Today surface modifications of titanium implants have become a development strategy of dental implants. The present study investigated the morphology (SEM), surface elemental analysis (EDX), surface roughness (AFM) and crystalline structure (XRD) of TiO2 film prepared via anodic oxidation of grade II commercially pure titanium specimens in different electrolytic solutions and times. Incubation ...