Pharmacoeconomic/outcomes research (PE/OR) fellowships have been in existence for more than 10 years in response to the rising demand for expertise in economic evaluation.1-4 The first fellowship in PE/OR began in 19891; however, finding detailed information about these programs is difficult for several reasons. First, quantifying PE/OR programs is a challenge due to their increasing number in ...

the concepts of SIRS and CARS still exist, although the notion that CARS represents a reaction to SIRS has been challenged [3, 4] . In this theme issue of the Journal of Innate Immunity, current knowledge of several aspects of the SIRS and CARS concepts are reviewed in 7 articles; the issue is completed by 3 original articles about these topics. Kumpf and Schumann [5] summarize data on genetic ...

Background Rheumatoid factor-positive subtype of juvenile idiopathic arthritis (RF+ JIA) is a relatively rare condition (5-7% all cases JIA), but associated with poor prognosis. For these patients (pts), it extremely important to timely prescribe adequate therapy, including biologics (B), prevent rapid progression and early disability. Objectives To analyze in retrospective study the rate usage...

Introduction. Endothelial dysfunction (ED) makes a significant contribution to the pathogenesis of rheumatoid arthritis (RA). However, changes vasomotor function (VF) in patients with reduction disease activity have not been studied enough. Objective – study VF RA and reduce activity, clarify role serological profile presence arterial hypertension (AH) formation dysfunction. Materials methods. ...

T he four major critical care societies in the United States—the American Association of Critical Care Nurses (AACN), the American College of Chest Physicians (ACCP), the American Thoracic Society (ATS), and the Society of Critical Care Medicine (SCCM)—have united in their efforts to address the manpower shortage of health-care providers who care for the critically ill. This is one of the most ...

INTRODUCTION The revised shared epitope (SE) concept in rheumatoid arthritis (RA) is based on the presence (S) or absence (X) of the SE RAA amino acid motif at positions 72 to 74 of the third hypervariable region of the various human leucocyte antigen (HLA)-DRB1 alleles. The purpose of this study was to investigate SE subtypes on the basis of the American College of Rheumatology 1987 revised cr...

In the January 2004 issue of CHEST, Drs. Irvin and Kaminsky1 wrote an editorial regarding the American Thoracic Society (ATS)/American College of Chest Physicians (ACCP) statement on cardiopulmonary exercise testing (CPET) published in the American Journal of Respiratory and Critical Care Medicine in January of 2003.2 In their article, they point out that the data generated from CPET are easily...