Two experiments are presented that measure the acuity of binaural processing of modulated interaural level differences (ILDs) using psychoacoustic methods. In both experiments, dynamic ILDs were created by imposing an interaurally antiphasic sinusoidal amplitude modulation (AM) signal on high-frequency carriers, which were presented over headphones. In the first experiment, the sensitivity to d...

KEY POINTS Cardiac vagal tone is a strong predictor of health, although its central origins are unknown. Respiratory-linked fluctuations in cardiac vagal tone give rise to respiratory sinus arryhthmia (RSA), with maximum tone in the post-inspiratory phase of respiration. In the present study, we investigated whether respiratory modulation of cardiac vagal tone is intrinsically linked to post-in...

WINTER, J. C., R. A. FILIPINK, D. TIMINERI, S. E. HELSLEY AND R. A. RABIN. The paradox of 5-methoxyN,N -dimethyltryptamine: An indoleamine hallucinogen that induces stimulus control via 5-HT 1 A receptors . PHARMACOL BIOCHEM BEHAV 65 (1) 75–82, 2000.—Stimulus control was established in rats trained to discriminate either 5-methoxyN,N -dimethyltryptamine (3 mg/kg) or ( 2 )-2,5-dimethoxy-4-methyl...

This paper considers discrete multitone (DMT) modulation for multiuser communications where different users are supported by the same system. These users may have differing quality of service (QoS) requirements, as quantified by their respective bit rate and symbol error rate specifications. Our goal is to minimize the transmitted power given the QoS specifications for the different users, subj...

Chronic contractile activation, or tone, in asthma coupled with continuous stretching due to breathing may be involved in altering the contractile function of airway smooth muscle (ASM). Previously, we (11) showed that cytoskeletal remodeling and stiffening responses to acute (2 h) localized stresses were modulated by the level of contractile activation of ASM. Here, we investigated if altered ...

N,N-dimethyltryptamine, or DMT, is an endogenous psychoactive chemical that has been shown through repeated human subject experimentation to provide the subject with a perception of an 'alternate reality'. When administered a sufficient DMT dose, subjects have reported the presence of intelligent beings that do not appear to be the projections of their subconscious in the Freudian sense. Furthe...

OBJECTIVE In MS, Socio-Economic status (SES) may influence healthcare and access to disease-modifying treatments (DMTs). Optimising delays to switch patients to a second-line DMT may hamper disease progression most effectively and achieve long term disease control. The objective of this study is to identify the influence of SES on the delay between first and second line DMT in RRMS patients, in...

BACKGROUND Functional MRI (fMRI) basic cognitive paradigms such as the n-back have been shown to detect cognitive impairment (CI) in Multiple Sclerosis (MS). The immediate memory task/delayed memory task (IMT/DMT) detects varying degrees of working memory (WM) by alternating three levels of complexity and two levels of WM delay. This paradigm has not been evaluated in MS nor validated against s...