BACKGROUND AND PURPOSE The aim of the present study was to examine resource utilization during a 12-month period after acute stroke in elderly patients randomized to care in an acute stroke unit integrated with a care continuum compared with conventional care in general medical wards. A secondary aim was to describe costs related to the severity of stroke. METHODS Two hundred forty-nine conse...

This study analyses the concept of cost functions for semi-automated Straddle Carrier (SC), Rubber Tyred Gantry (RTG) and automated Rail Mounted Gantry (RMG) container yard operating cranes. It develops a generic cost based model for a pair-wise comparison, analysis and evaluation of economic efficiency and effectiveness of container yard equipment to be used for decision-making by terminal pla...

BACKGROUND Multiple sclerosis (MS) is chronic and debilitating, afflicts patients in the prime of their lives, and requires costly, decades-long disease management. MS prevalence is increasing, and treatment with new drug therapies is expensive. OBJECTIVES The objectives of this analysis were to (1) determine the average total and component direct medical costs incurred in the treatment of MS...

OBJECTIVE To estimate the total annual cost due to Chronic Hepatitis B (CHB)-related diseases imposed on each patient and his/her family in Beijing and Guangzhou, China. METHODS Economic burden of CHB-related diseases (CHB, compensated cirrhosis, decompensated cirrhosis, and hepatocellular carcinoma) were examined. A retrospective cohort of 328 patients in Beijing and 271 in Guangzhou were id...

OBJECTIVES To compare the annual costs of treating schizophrenia with four atypical antipsychotics-olanzapine, risperidone, quetiapine and ziprasidone and one typical antipsychotic: haloperidol in Thailand MATERIAL AND METHOD The present study used a cost analysis model. The model simulated treatment of schizophrenics for 12 months with the data from international literature review. A compreh...

We develop a model to determine an integrated vendor-buyer inventory policy for items with imperfect quality and planned backorders. The production process is imperfect and produces a certain number of defective items with a known probability density function. The vendor delivers the items to the buyer in small lots of equally sized shipments. Upon receipt of the items, the buyer will conduct a...

Bender et al. (SPAA 2013) have proposed a theoretical framework for testing in contexts where safety mistakes must be avoided. Testing in such a context is made by machines that need to be often calibrated. Given that calibration costs, it is important to study policies minimizing the calibration cost while performing all the necessary tests. We focus on the single-machine setting and we extend...

Economic optimization of shell and tube heat exchanger (STHE) is presented in this paper. To increase the rate of heat transfer, copper oxide (CuO) nanoparticle is added into the tube side fluid and their optimum results are compared with the case of without additive nanoparticle. Total annual cost (TAC) is selected as fitness function and nine decision variables related to the heat exchanger p...

The main objective of the distribution system planning is to determine the substation location, size and its service area, number of feeders and their routes. The planning problem is solved by classical methods to non traditional soft computing techniques, hence in this work, soft computing technique known as Simulated Annealing is used. Simulated Annealing is a thermal process for obtaining lo...