background:    previous studies suggest total hip arthroplasty may have some benefits compared to hemi-arthroplasty for displaced intracapsular femoral neck fractures in patients more than 60 years of age. the primary research question of our study was whether in-hospital adverse events, post-operative length of stay (los) and mortality in patients 60 year of age or older differed between total...

is generally believed that the sex chromatin which is found in the cells of 'Lammalian Eemales represents a genetically inactive X chromosome (LYON 1961 ; RUSSELL 1961 ) iwhich is heterochromatic and is replicated out of synchrony with the other X (ATKINS, TAFT and DALAL 1962; GRUMBACH, MORISHIMA and TAYLOR 1963; OHNO and CATTANACH 1962). According to the single-active-X hypothesis, inactivatio...

We discover a new type of nonequilibrium phase transition in model chromatin dynamics, which accounts for the coherent motions that have been observed experiment. The motion is due to long-range cooperation molecular motors tethered chromatin. Cooperation occurs if each motor acts simultaneously on polymer and surrounding solvent, exerting them equal opposite forces. This drives flow solvent pa...

Deciphering the factors that control chromatin fiber structure is key to understanding fundamental chromosomal processes. Although details remain unknown, it is becoming clear that chromatin is polymorphic depending on internal and external factors. In particular, different lengths of the linker DNAs joining successive nucleosomes (measured in nucleosome-repeat lengths or NRLs) that characteriz...

Concatameric 5 S rDNA templates reconstituted in vitro into nucleosomal arrays provide very popular chromatin models for many kinds of studies. Here, atomic force microscopy is used to determine the population distributions for one such nucleosomal array, the 172-12, reconstituted to various subsaturated levels with nonacetylated or hyperacetylated HeLa histones. This array is a model for short...