The aim of this work was to determine the effect of dietary n - 3 PUFA on oxidant/antioxidant status, in vitro very low and low density lipoprotein (VLDL-LDL), and VLDL-LDL-fatty acid composition in macrosomic pups of diabetic mothers. We hypothesized that n - 3 PUFA would improve oxidative stress in macrosomia. Diabetes was induced in female Wistar rats fed with the ISIO diet (control) or with...

The aim of this study was to evaluate for the cytotoxicity, genotoxicity and antioxidant/oxidant activity of GYZ on human peripheral blood lymphocytes (PBLs). Guaiazulene (GYZ) was added into culture tubes at various concentrations (0-400 μg/mL). Cytotoxicity against the human lymphocytes cultures was examined by lactate dehydrogenase (LDH) release assay. The proliferative response was estimate...

BACKGROUND AND AIM: Recurrent Aphthous Stomatitis (RAS) as a common oral lesion can be related to oxidative stress. The aim of this study was to review the antioxidant-oxidant status of saliva in patients with RAS.METHODS: In this review study, all English and Persian articles were searched by relevant keywords from the PubMed, science direct, Cochrane, Scopus and Sid databases from 1995 ...

To evaluate the presence of free radicals in various drugs used in ophthalmology. Twenty five samples of drugs that are used by intracameral or intravitreal route, eleven samples of drugs used as fortified eye drop, thirty samples of topical commercial preparations that are used as long term, and eight samples of autologous serum were analyzed for total free radical presence using a kit for tot...

OBJECTIVE Oxidative stress is considered to be the main factor in the development of diabetic complications and tissue injury. our objective was to investigate and compare the oxidant/antioxidant conditions and detoxification mechanisms of the liver, lung, kidney, cardiac tissues, and mitochondria of rats with diabetes induced by streptozocin (STZ). METHODS Rats with diabetes induced by strep...

BACKGROUND/AIMS We aimed to analyze the efficiency of a novel treatment approach, long-term synbiotic supplementation, in addition to lifestyle changes in children with non-alcoholic fatty liver disease (NAFLD). MATERIALS AND METHODS The study included children with NAFLD (n=28) and a healthy control group (n=30). Children with NAFLD were given 1 capsule/day of synbiotics. Anthropometric para...

BACKGROUND The role of free oxygen radicals in inflammatory conditions is well known. Free radicals cause lipid peroxidation of cellular membranes resulting in cell death. The purpose of this study was to investigate the levels of total anti-oxidant status (TAS), as a marker of anti-oxidant defense system and malondialdehyde (MDA), as a marker of oxidative stress, in the plasma of patients with...

calendula officinalis (family compositae) flowers are recognized as safe substance for food use by food and drug administration. present study was aimed to determine the modulatory effect of floral extracts of c. officinalis administrations on mean blood glucose (mbg), per cent glycosylated hemoglobin (hba1c), lipid profile [(total cholesterol (tc), triglycerides (tg), low and high density lipo...

Depression is one of the prevalent psychiatric diseases in Turkey and world. Fluvoxamine a strong selective serotonin reuptake inhibitor (SSRI) that used as an antidepressant. No study investigating doses treatment may lead to disruption oxidant-antioxidant balance on cellular level addition its beneficial effects has been found literature. For this purpose, by creating application groups at 7....